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5,983 papers
Intrinsic plasmon canalization in the biaxial van der Waals crystal MoOCl2

Farid Aghashirinov, Andrea Mancini, Lin Nan, Giacomo Venturi et al.

Abstract Anisotropic polaritons in low-symmetry crystals allow for subwavelength confinement and directional routing of light. The most extreme form of such anisotropy arises at the topological transition between elliptical and hyperbolic dispersion, where the isofrequency contours collapse into parallel lines and polaritons propagate in a diffractionless, beam-like fashion. Th…

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Hidden spin-valley locking stabilizes nanosecond spin polarization in 2D perovskites

Rayan Chakraborty, Yifan Dong, Jacob L. Shelton, Kelsey Garden et al.

Room-temperature spin control in semiconductors is fundamental to spin-optoelectronics. Although inversion symmetry breaking offers one path for spin control in semiconductors, strong spin dephasing at elevated temperatures remains a persistent limitation. Hidden spin polarization without global symmetry breaking provides another promising material design strategy, but robust s…

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Spontaneous and indefinite blinking in upconverting nanoparticles for ångström-precision multicolour super-resolution imaging

Saptarshi Mandal, Harrison W. Toll, Kaibo Ma, Irmuun Tommy Altankhuyag et al.

Single-molecule localization microscopy enables high-resolution biological imaging, but its precision is limited by the rapid photobleaching of conventional fluorophores. Multicolour imaging is further constrained by the need for spectrally distinct dyes requiring separate excitations or sequential acquisition. Here we show that small (~10 nm) upconverting nanoparticles can be …

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Strain-isolated microneedles for ambulatory hormonal and metabolic monitoring

Gwangmook Kim, Seokjoo Cho, Hyunah Ahn, Canran Wang et al.

Hormones and metabolites jointly regulate physiology yet their dynamic interplay remains difficult to resolve due to the lack of technologies for continuous, multiplexed monitoring. Microneedle biosensors that access dermal interstitial fluid offer a minimally invasive approach to molecular profiling, but deployment is limited by trade-offs between fabrication scalability and p…

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Integrated blue ZnSe/ZnS quantum dot lasers on a silicon nitride platform

Jinhua He, Korneel Molkens, Dries Van Thourhout, Pieter Geiregat et al.

On-chip blue lasers are essential for data storage, quantum photonics, optical communications and lab-on-chip sensing. Existing GaN-based devices deliver high performance but demand lattice-matched substrates, involve complex architectures and suffer from high optical losses in the visible range. Here we extend the CMOS-compatible fabrication methodology used to incorporate emi…

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Self-assembled contacts for high-yield molecular devices

Sarah O. Spector, Peter F. Satterthwaite, Maxwell Conte, Teddy Hsieh et al.

With their atomic precision and synthetically tailorable properties, molecules offer new possibilities for emerging computing, sensing, optical and quantum technologies. However, the scalable, damage-free integration of molecules into active devices with atomic-scale control remains a critical challenge due to incompatibility with existing top-down fabrication processes. Here w…

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Coherent room-temperature dipole synchronization in plasmonic nanocavities

Rakesh Arul, Piper Fowler-Wright, Lille Børresen, Brendon W. Lovett et al.

Abstract Plasmonic nanocavities enable the synchronization of spatially distant emissive dipoles through strong near-field coupling in subnanometre gaps. Yet, it remains unclear how collective phase order can emerge in nanoscale optical systems where dissipation, disorder and ultrafast radiative loss normally suppress long-lived coherence. Here we report the formation of a room…

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Nature Nanotechnology·2026Open access
Magnetic brightening and nanoscale imaging of spin-polarized helical edge modes in ZrTe5

Samuel Haeuser, Richard H. J. Kim, Lin-Lin Wang, Thomas Koschny et al.

Efficient charge transport remains a fundamental challenge for nanoelectronic devices, as their performance is constrained by high dissipation and the impedance mismatch between high-frequency signal sources and nanoscale circuit interfaces. Although topologically protected helical edge modes offer a dissipationless and backscattering-resilient alternative, achieving nanoscale …

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Immunostimulatory lipogel implant enhances cancer immunotherapy

Ying Zhang, Enlai Wang, Shiyang Li, Yufan Yao et al.

Cancer stem-like cells contribute to innate tumour immunoresistance and an immunosuppressive tumour microenvironment, leading to poor responses to immune checkpoint inhibitors. Chemotherapeutic agents can elicit tumour immunogenicity by inducing immunogenic cell death to reinforce the therapeutic efficacies of immune checkpoint inhibitors, but suffer from inefficient immunogeni…

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Computationally guided design of bioactive nanostructures for targeted clearance of amyloid-β aggregates in Alzheimer’s disease

Tianyi Qi, Jingxuan Fu, Yajie Wang, Ming Zhao et al.

Targeted clearance of pre-existing amyloid-β (Aβ) aggregation remains a central challenge in Alzheimer's disease (AD) therapy. Here we report a computationally guided protein-gold hybrid nanostructure, Aβ3FTnAu, that integrates Aβ-recognition motifs into self-assembled human ferritin nanocages containing structurally defined gold nanoclusters composed of 12 gold atoms wit…

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Catalytic profiling of extracellular vesicles maps altered cancer metabolism

Qingchang Chen, Yan Zhang, Auginia Natalia, Jun Zhou et al.

Current technologies for measuring cancer metabolism have limited clinical utility, as they require invasive tissue sampling and lack analytical versatility. Here, we report a programmable nanotechnology platform that directly profiles extracellular vesicles (EVs) in patient biofluids to comprehensively capture metabolic alterations within the tumour milieu. This technology, te…

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