journal article·2012-03-26Open access

Stimuli-Responsive Polymer Brushes for Flow Control through Nanopores

Shashishekar P. Adiga, Donald W. Brenner

Abstract

Responsive polymers attached to the inside of nano/micro-pores have attracted great interest owing to the prospect of designing flow-control devices and signal responsive delivery systems. An intriguing possibility involves functionalizing nanoporous materials with smart polymers to modulate biomolecular transport in response to pH, temperature, ionic concentration, light or electric field. These efforts open up avenues to develop smart medical devices that respond to specific physiological conditions. In this work, an overview of nanoporous materials functionalized with responsive polymers is given. Various examples of pH, temperature and solvent responsive polymers are discussed. A theoretical treatment that accounts for polymer conformational change in response to a stimulus and the associated flow-control effect is presented.
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Research context

OpenAlex topics: Analytical Chemistry and Sensors · Polymer Surface Interaction Studies · Microfluidic and Capillary Electrophoresis Applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Kodak Research Laboratories, Eastman Kodak Company, Rochester, NY 14620, USA

Department of Materials Science and Engineering, North Carolina State University, Raleigh, NC 27695, USA

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