Poly(2-hydroxyethyl methacrylate)-quercetin Conjugate as Biomaterial in Ophthalmology: An “ab initio” Study
Source abstract
Abstract
A novel polymeric material with antioxidant properties and suitable for ophthalmic application was synthesized by free radical grafting reaction between 2-hydroxyethyl methacrylate and quercetin. The presence of quercetin in the polymeric chain was confirmed by FT-IR and UV-Vis analyses, while an estimation of the amount of quercetin bound per gram of polymer was obtained by the Folin-Ciocalteu assay. The conjugate shows high biocompatibility (HET-CAM assay) and antioxidant and anti-inflammatory properties which were extensively investigated by specific in vitro tests.
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Research context
OpenAlex topics: Photodynamic Therapy Research Studies · Free Radicals and Antioxidants · Photochromic and Fluorescence Chemistry
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Dipartimento di Scienze Farmaceutiche, Università della Calabria, Edificio Polifunzionale, 87036 Arcavacata di Rende (CS), Italy
Macrofarm Srl, Università della Calabria, Edificio Polifunzionale, 87036 Arcavacata di Rende (CS), Italy
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