Enhancing Guided Bone Regeneration with a Novel Carp Collagen Scaffold: Principles and Applications
Source abstract
Abstract
Bone defects resulting from trauma, surgery, and congenital, infectious, or oncological diseases are a functional and aesthetic burden for patients. Bone regeneration is a demanding procedure, involving a spectrum of molecular processes and requiring the use of various scaffolds and substances, often yielding an unsatisfactory result. Recently, the new collagen sponge and its structural derivatives manufactured from European carp (Cyprinus carpio) were introduced and patented. Due to its fish origin, the novel scaffold poses no risk of allergic reactions or transfer of zoonoses and additionally shows superior biocompatibility, mechanical stability, adjustable degradation rate, and porosity. In this review, we focus on the basic principles of bone regeneration and describe the characteristics of an “ideal” bone scaffold focusing on guided bone regeneration. Moreover, we suggest several possible applications of this novel material in bone regeneration processes, thus opening new horizons for further research.
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Research context
OpenAlex topics: Bone Tissue Engineering Materials · Periodontal Regeneration and Treatments · Bone and Dental Protein Studies
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Oral and Maxillofacial Surgery, 1st Faculty of Medicine and General University Hospital in Prague, Charles University, 12108 Prague, Czech Republic
Funding
Ministry of Health in the Czech Republic
References (100+)
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