journal article·2021

Recent developments in mussel-inspired materials for biomedical applications

Natan Roberto Barros, Yi Chen, Vahid Hosseini, Weiyue Wang, Rohollah Nasiri, Mahboobeh Mahmoodi, Ezgi Pinar Yalcintas, Reihaneh Haghniaz, Marvin Magan Mecwan, Solmaz Karamikamkar, Wei Dai, Shima A. Sarabi, Natashya Falcone, Patric Young, Yangzhi Zhu, Wujin Sun, Shiming Zhang, Junmin Lee, Kangju Lee, Samad Ahadian, Mehmet Remzi Dokmeci, Ali Khademhosseini, Han-Jun Kim

Biomaterials Science· Volume 9· Issue 20
Publisher page

Abstract

Over the decades, researchers have strived to synthesize and modify nature-inspired biomaterials, with the primary aim to address the challenges of designing functional biomaterials for regenerative medicine and tissue engineering. Among these challenges, biocompatibility and cellular interactions have been extensively investigated. Some of the most desirable characteristics for biomaterials in these applications are the loading of bioactive molecules, strong adhesion to moist areas, improvement of cellular adhesion, and self-healing properties. Mussel-inspired biomaterials have received growing interest mainly due to the changes in mechanical and biological functions of the scaffold due to catechol modification. Here, we summarize the chemical and biological principles and the latest advancements in production, as well as the use of mussel-inspired biomaterials. Our main focus is the polydopamine coating, the conjugation of catechol with other polymers, and the biomedical applications that polydopamine moieties are used for, such as matrices for drug delivery, tissue regeneration, and hemostatic control. We also present a critical conclusion and an inspired view on the prospects for the development and application of mussel-inspired materials.
Source: openalex_inverted_index · Quality: candidate unverified · Source record ↗

Research context

OpenAlex topics: Bone Tissue Engineering Materials · Polymer Surface Interaction Studies · Electrospun Nanofibers in Biomedical Applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Terasaki Institute for Biomedical Innovation, Los Angeles, CA 90024, USA

School of Materials Science and Engineering, South China University of Technology, Guangzhou 510006, P. R. China

Guangzhou Redsun Gas Appliance CO., Ltd, Guangzhou 510460, P. R. China

Guangdong Engineering & Technology Research Center for Quality and Efficacy Reevaluation of Post-Market Traditional Chinese Medicine, Guangdong Key Laboratory of Plant Resources, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, P. R. China

Department of Biomedical Engineering, Yazd Branch, Islamic Azad University, Yazd, Iran

Department of Research and Design, Beijing Biosis Healing Biological Technology Co., Ltd, Daxing District, Biomedical Base, Beijing 102600, P. R. China

Department of Mechanical and Aerospace Engineering, University of California Los Angeles, Los Angeles, CA 90095, USA

Department of Electrical and Electronic Engineering, The University of Hong Kong, China

Department of Healthcare and Biomedical Engineering, Chonnam National University, Yeosu 59626, South Korea

Funding

National Institutes of Health

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