Effect of polydimethylsiloxane (PDMS) coating on TiO2-based MALDI matrix for dimethyl methylphosphonate (DMMP) analysis
Source abstract
Abstract
Abstract TiO2 nanoparticles were used as MALDI matrix for detecting dimethyl methylphosphate (DMMP) and its efficiency, in terms of DMMP signal intensity in the MALDI-MS analysis, was compared with that of polydimethylsiloxane (PDMS)-coated TiO2 matrix. Intensity of the DMMP signal in the MALDI-MS analysis was significantly increased by using PDMS-coated TiO2 matrix instead of bare ones. It was verified using FT-IR that the enhanced DMMP signal upon PDMS coating on TiO2 matrix is a result of weaker interactions between DMMP molecule and the PDMS-covered surface than that of bare TiO2. A weaker DMMP-matrix interaction can facilitate desorption of DMMP from the matrix surface in the MALDI process, yielding a higher sensitivity to DMMP in the MALDI-MS.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Mass Spectrometry Techniques and Applications · Analytical chemistry methods development · Biosensors and Analytical Detection
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
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