Microarray of neuroblastoma cells on the selectively functionalized nanocrystalline diamond thin film surface
Source abstract
Abstract
Abstract Nanocrystalline diamond (NCD) film surfaces were modified with fluorine or oxygen by plasma treatment in an O 2 or C 3 F 8 gas environment in order to induce wettability. The oxygenated-NCD (O-NCD) film surface was hydrophilic and the fluorinated-NCD (F-NCD) surface was hydrophobic. The efficiency of early cell adhesion, which is dependent on the wettability of the cell culture plate and necessary for the growth and proliferation of cells, was 89.62 ± 3.92% on the O-NCD film and 7.78 ± 0.77% on the F-NCD film surface after 3 h of cell culture. The wettability of the NCD film surface was artificially modified using a metal mask and plasma treatment to fabricate a micro-pattern. Four types of micro-patterns were fabricated (line, circle, mesh, and word) on the NCD film surface. We precisely arrayed the neuroblastoma cells on the micro-patterned NCD film surfaces by controlling the surface wettability and cell seeding density. The neuroblastoma cells adhered and proliferated along the O-NCD film surface.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Diamond and Carbon-based Materials Research · Polymer Surface Interaction Studies · Force Microscopy Techniques and Applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (37)
Show source-provided references
1. Photoelectrochemical properties of semiconductor diamond10.1016/0022-0728(87)80093-1 ↗
2. Polycrystalline diamond electrodes: basic properties and applications as amperometric detectors in flow injection analysis and liquid chromatography10.1016/S0003-2670(99)00400-6 ↗
3. The properties and applications of nanodiamonds10.1038/nnano.2011.209 ↗
4. pH-sensitive diamond field-effect transistors (FETs) with directly aminated channel surface10.1016/j.aca.2006.04.051 ↗
5. Surface-modified diamond field-effect transistors for enzyme-immobilized biosensors10.1143/JJAP.43.L814 ↗
6. DNA-modified nanocrystalline diamond thin-films as stable, biologically active substrates10.1038/nmat779 ↗
7. The surface properties of nanocrystalline diamond and nanoparticulate diamond powder and their suitability as cell growth support surfaces10.1016/j.biomaterials.2008.07.023 ↗
8. Diamond for bio-sensor applications10.1088/0022-3727/40/20/S21 ↗
9. Impact of differently modified nanocrystalline diamond on the growth of neuroblastoma cells10.1016/j.nbt.2014.06.008 ↗
10. Impact of diamond nanoparticles on neural cells10.1016/j.mcp.2014.10.005 ↗
11. Promoting neuron adhesion and growth10.1016/S1369-7021(08)70088-9 ↗
12. Ordered growth of neurons on diamond10.1016/j.biomaterials.2003.11.006 ↗
13. Patterned growth of neuronal cells on modified diamond-like carbon substrates10.1016/j.biomaterials.2008.03.001 ↗
14. Emergent functional properties of neuronal networks with controlled topology10.1371/journal.pone.0034648 ↗
15. 2D spatially controlled polymer micro patterning for cellular behavior studies10.1016/j.apsusc.2010.09.113 ↗
16. Micro-pattern guided adhesion of osteoblasts on diamond surfaces10.3390/s90503549 ↗
17. Pattern technologies for structuring neuronal networks on MEAs
18. The competitive effects of serum proteins on cell adhesion10.1242/jcs.71.1.17 ↗
19. Adhesion strength of diamond films on heat-treated WC–Co cutting tools10.1016/j.diamond.2007.09.003 ↗
20. Surface and bioproperties of nanocrystalline diamond/amorphous carbon nanocomposite films10.1016/j.tsf.2007.05.054 ↗
21. Neuroblastoma cells grown on fluorine or oxygen treated graphene sheets10.1016/j.matlet.2014.06.013 ↗
22. Characterization of diamond films by Raman spectroscopy10.1557/JMR.1989.0385 ↗
23. Nanocrystalline diamond films: transmission electron microscopy and Raman spectroscopy characterization10.1016/S0925-9635(96)00743-1 ↗
24. Effect of the excitation wavelength on Raman scattering of microcrystalline diamond prepared in a low pressure inductively coupled plasma10.1063/1.373870 ↗
25. Synthesis of micro-or nano-crystalline diamond films on WC–Co substrates with various pretreatments by hot filament chemical vapor deposition10.1016/j.apsusc.2010.02.031 ↗
26. The mystery of the 1140cm−1 Raman line in nanocrystalline diamond films10.1016/j.carbon.2003.12.045 ↗
27. Analysis of the composite structures in diamond thin films by Raman spectroscopy10.1103/PhysRevB.41.3738 ↗
28. The origin of the broadband luminescence and the effect of nitrogen doping on the optical properties of diamond films10.1063/1.357508 ↗
29. Formation of carbon nitride films on Si (100) substrates by electron cyclotron resonance plasma assisted vapor deposition10.1063/1.112272 ↗
30. Detection of mismatched DNA on partially negatively charged diamond surfaces by optical and potentiometric methods10.1021/ja710167z ↗
31. Photochemical functionalization of diamond films10.1021/la0112561 ↗
32. Fluorination of polycrystalline diamond films and powders. An investigation using FTIR spectroscopy, SEM, energy-filtered TEM, XPS and fluorine-18 radiotracer methods10.1039/b006800o ↗
33. Effects of plasma treatment to nanofibers on initial cell adhesion and cell morphology10.1016/j.colsurfb.2013.08.031 ↗
34. Electrospun P (LLA-CL) nanofiber: a biomimetic extracellular matrix for smooth muscle cell and endothelial cell proliferation10.1016/j.biomaterials.2003.08.042 ↗
35. Osteoblast adhesion on biomaterials10.1016/S0142-9612(99)00242-2 ↗
36. Cell adhesion and growth on ultrananocrystalline diamond and diamond-like carbon films after different surface modifications10.1016/j.apsusc.2014.01.085 ↗
37. Understanding protein adsorption phenomena at solid surfaces10.1016/j.cis.2010.12.007 ↗