journal article·2026-02

The tether compound/backfiller ratio impacts protein pore formation in the artificial lipid membrane

Tadas Ragaliauskas, Martynas Talaikis, Ringailė Lapinskaitė, Rita Sadzevičienė, Jurgis Sūdžius, Vaidas Pudžaitis, Marija Jankunec, Rima Budvytytė, Linas Labanauskas

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OpenAlex topics: Lipid Membrane Structure and Behavior · Nanopore and Nanochannel Transport Studies · Advanced biosensing and bioanalysis techniques

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References (40)

Show source-provided references
1. Role of pore-forming toxins in bacterial infectious diseases10.1128/MMBR.00052-12 ↗
2. Staphylococcus aureus bacteraemia mortality: a systematic review and meta-analysis10.1016/j.cmi.2022.03.015 ↗
3. Understanding the diversity of membrane lipid composition10.1038/nrm.2017.138 ↗
4. Atomic force microscopy: a versatile tool to probe the physical and chemical properties of supported membranes at the nanoscale10.1016/j.chemphyslip.2012.10.005 ↗
5. Surface plasmon resonance for measuring interactions of proteins with lipids and lipid membranes10.1007/978-1-4939-9512-7_3 ↗
6. Tethered membrane architectures—design and applications10.3389/fmats.2018.00055 ↗
7. Tethered phospholipid bilayer membranes10.1016/bs.adplan.2015.01.003 ↗
8. Reconstitution of cholesterol-dependent vaginolysin into tethered phospholipid bilayers: implications for bioanalysis10.1371/journal.pone.0082536 ↗
9. Inerolysin and vaginolysin, the cytolysins implicated in vaginal dysbiosis, differently impair molecular integrity of phospholipid membranes10.1038/s41598-019-47043-5 ↗
10. Synthesis and characterization of novel anchorlipids for tethered bilayer lipid membranes10.1021/acs.langmuir.7b00778 ↗
11. Structural analysis of tethered bilayer lipid membranes10.1021/la100342k ↗
12. Molecular-scale structural and functional characterization of sparsely tethered bilayer lipid membranes10.1116/1.2709308 ↗
13. Membrane perforation by the pore-forming toxin pneumolysin10.1073/pnas.1904304116 ↗
14. Glycerol-based thiolipids for model membranes10.6001/chemija.2014.25.4.6 ↗
15. Fast formation of low-defect-density tethered bilayers by fusion of multilamellar vesicles10.1016/j.bbamem.2017.01.015 ↗
16. Formation of tethered bilayer lipid membranes on gold surface probed by in situ SEIRAS10.6001/chemija.2023.34.1.1 ↗
17. Speciation of adsorbed phosphate at gold electrodes: a combined surface-enhanced infrared absorption spectroscopy and DFT study10.1021/acs.jpclett.6b01342 ↗
18. WSXM: a software for scanning probe microscopy and a tool for nanotechnology10.1063/1.2432410 ↗
19. Split ring resonator sensors for infrared detection of single molecular monolayers10.1063/1.3194154 ↗
20. Structure and properties of tethered bilayer lipid membranes with unsaturated anchor molecules10.1021/la401132c ↗
21. Temperature dependence of the protein resistance of poly- and oligo(ethylene glycol)-terminated alkanethiolate monolayers10.1021/la010576h ↗
22. Molecular engineering of tethered bilayer lipid membranes for impedimetric detection of pore-forming toxins10.1016/j.electacta.2024.145226 ↗
23. Characterization of a series of self-assembled monolayers of alkylated 1-thiaoligo(ethylene oxides)4-8 on gold10.1021/la9916833 ↗
24. Molecular conformation in oligo(ethylene glycol)-terminated self-assembled monolayers on gold and silver surfaces determines their ability to resist protein adsorption10.1021/jp972635z ↗
25. Structure and conformation in mixtures of methyl-terminated poly(ethylene oxide) and water. Principal component analysis and band fitting of infrared absorptions10.1021/jp905149z ↗
26. Water structure in the submembrane region of a floating lipid bilayer: the effect of an ion channel formation and the channel blocker10.1021/acs.langmuir.9b03271 ↗
27. A new lipid anchor for sparsely tethered bilayer lipid membranes10.1021/la8033275 ↗
28. Functional incorporation of the pore forming segment of AChR M2 into tethered bilayer lipid membranes10.1016/j.bbamem.2007.02.006 ↗
29. Classification of gallstones using Fourier-transform infrared spectroscopy and photography10.1186/s40824-018-0128-8 ↗
30. Böhlig, FTIR-spectroscopic characterization of phosphocholine-headgroup model compounds10.1016/S0022-2860(00)00830-9 ↗
31. Fourier transform infrared spectroscopy as a probe for the study of the hydration of lipid self-assemblies. I. Methodology and general phenomena10.1002/(SICI)1520-6343(1998)4:4<267::AID-BSPY5>3.0.CO;2-# ↗
32. Quantitative determination of surface concentration of protein with surface plasmon resonance using radiolabeled proteins10.1016/0021-9797(91)90284-F ↗
33. CryoEM structures of membrane pore and prepore complex reveal cytolytic mechanism of pneumolysin10.7554/eLife.23644 ↗
34. Solvent effects on composition and structure of thiolipid molecular anchors for tethering phospholipid bilayers10.1016/j.apsusc.2020.145268 ↗
35. In-plane homogeneity and lipid dynamics in tethered bilayer lipid membranes (tBLMs)10.1039/b919988h ↗
36. Membrane lateral mobility obstructed by polymer-tethered lipids studied at the single molecule level10.1529/biophysj.104.050559 ↗
37. Inactivation and activity of cholesterol-dependent cytolysins: what structural studies tell us10.1016/j.str.2005.04.019 ↗
38. Structure of functional Staphylococcus aureus α-hemolysin channels in tethered bilayer lipid membranes10.1016/j.bpj.2008.11.020 ↗
39. Electrochemical impedance spectroscopy of tethered bilayer membranes10.1021/la204054g ↗
40. Kinetic defects induced by melittin in model lipid membranes: a solution atomic force microscopy study10.1021/acs.jpcb.6b02332 ↗