Construction of heparinylated multilayer films on Ti O via streptavidin/biotin interaction
Source abstract
Abstract
Abstract Construction of heparinylated multilayer films on Ti O via streptavidin/biotin interaction was conducted in the present study. An organic layer of 3-aminopropylphosphonic acid (APP) was first introduced on Ti O by self-assembling, and then biotin was immobilized by photochemical methods. So streptavidin and biotinylated heparin were assembling through biorecognition, and a desired 6-layer heparinylated multilayer was obtained through layer-by-layer driven by streptavidin/biotin interaction. The in vitro platelet adhesion and activation were investigated by a static platelet adhesion test. The clotting time was examined by activated partial thromboplastin time (APTT). Results show that the heparinylated multilayer coated Ti O can significantly decrease platelet adhesion and activation, and prolong clotting time of APTT compared to untreated Ti O, which indicates the heparinylated multilayer coated Ti O displays more excellent anticoagulation performance than that of the bare Ti O.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Polymer Surface Interaction Studies · Electrospun Nanofibers in Biomedical Applications · Hemostasis and retained surgical items
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (31)
Show source-provided references
1. Immobilization of heparin on PVDF membranes with microporous structures10.1016/j.memsci.2004.07.028 ↗
2. Immobilization of heparin on polysulfone surface for selective adsorption of low-density lipoprotein (LDL)10.1016/j.actbio.2009.08.039 ↗
3. Interactions of leukocytes and platelets with poly(lysine/leucine) immobilized on tetraethylene glycol-terminated self-assembled monolayers10.1016/j.actbio.2011.01.013 ↗
4. Covalently immobilized thrombomodulin inhibits coagulation and complement activation of artificial surfaces in vitro10.1016/j.biomaterials.2003.12.014 ↗
5. Immobilization of NaIO4-treated heparin on PEG-modified 316L SS surface for high anti-thrombin-III binding10.1002/jbm.a.31662 ↗
6. Anticoagulant-free Genius haemodialysis using low molecular weight heparin-coated circuits10.1093/ndt/gfi293 ↗
7. Heparin coating on ureteral double J stents prevents encrustations: an in vivo case study10.1089/end.2007.0218 ↗
8. Can heparin immobilized surfaces maintain nonthrombogenic activity during in vivo long-term implantation10.1097/00002480-199609000-00032 ↗
9. Heparin release from thermosensitive polymer coatings: in vivo studies10.1002/jbm.820290705 ↗
10. Enhanced patency of small-diameter tubings after surface immobilization of heparin fragments. A study in the dog10.1002/jbm.820230302 ↗
11. Antithrombin and heparin10.1016/S1357-4310(95)91494-3 ↗
12. Effectiveness of heparin in preventing thrombin generation and thrombin activity in patients undergoing coronary intervention10.1053/hj.1999.v137.91541 ↗
13. Inhibition of coagulation and platelet adhesion to extracellular matrix by unfractionated heparin and a low molecular weight heparin10.1007/BF01732879 ↗
14. Construction of pegylated multilayer architectures via (strept)avidin/biotin interactions10.1016/j.msec.2006.05.042 ↗
15. Layer-by-layer assembly of multilayer films composed of avidin and biotin-labeled antibody for immunosensing10.1016/S0956-5663(02)00114-8 ↗
16. Surface plasmon resonance imaging measurements of DNA hybridization adsorption and streptavidin/DNA multilayer formation at chemically modified gold surfaces10.1016/j.colsurfa.2011.05.021 ↗
17. Brave new (strept)avidins in biotechnology10.1016/j.tibtech.2007.04.001 ↗
18. Photochemical immobilization of bovine serum albumin on TiO and evaluations in vitro and in vivo10.1016/j.apsusc.2008.06.112 ↗
19. Use of the activated partial thromboplastin time for heparin monitoring10.1309/N7RA-D6XN-9EQX-ABJ9 ↗
20. Role of platelets in blood-biomaterial interactions
21. How the biotin–streptavidin interaction was made even stronger: investigation via crystallography and a chimaeric tetramer10.1042/BJ20101593 ↗
22. Preparation and anticoagulation activity of sodium cellulose sulfate10.1016/j.ijbiomac.2007.05.007 ↗
23. A sulfated fucan from the brown alga Laminaria cichorioides has mainly heparin cofactor II-dependent anticoagulant activity10.1016/j.carres.2007.06.019 ↗
24. The influence of molecular mass of sulfated propylene glycol ester of low-molecular-weight alginate on anticoagulant activities10.1016/j.eurpolymj.2007.04.015 ↗
25. Interaction of blood components with heparin-immobilized polyurethanes prepared by plasma glow discharge10.1163/15685620152691878 ↗
26. In vitro blood compatibility of heparin-immobilized polyurethane containing ester groups in the side chain10.1023/B:JMSM.0000046389.87287.3f ↗
27. Surface immobilization of chondroitin 6-sulfate/heparin multilayer on stainless steel for developing drug-eluting coronary stents10.1016/j.colsurfb.2007.07.004 ↗
28. Blood compatibility and permeability of heparin-modified polysulfone as potential membrane for simultaneous hemodialysis and LDL removal10.1002/mabi.201000278 ↗
29. Platelet adhesion and activation on an amphoteric chitosan derivative bearing sulfonate groups10.1016/S0927-7765(98)00005-8 ↗
30. Selective adhesion of platelets on a polyion complex composed of phospholipid polymers containing sulfonate groups and quarternary ammonium groups10.1002/jbm.820281113 ↗
31. Polyurethanes bearing pendant amino acids: fibrinogen adsorption and coagulant properties10.1002/jbm.820260804 ↗