Highly sensitive DNA sensor based on polypyrrole nanowire
Source abstract
Abstract
Abstract This paper describes the development of a DNA sensor based on polypyrrole nanowire. By using potentiostatic technique, in the presence of gelatin as the soft mold, the polypyrrole nanowires were synthesized on the surface of the micro-sensor. The surface enhanced Raman spectroscopy shows that the N H ends of the polypyrrole nanowires orientate upward from the surface facilitating the DNA probe immobilization through the simple linkage with the phosphate groups of the probe DNA. The label-free signal readout was carried out by lock-in amplifier technique. The response time of the DNA sensor is 10 s and the measurement time was 5 min. The lowest detectable concentration of Escherichia coli DNA was 0.1 nM.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Conducting polymers and applications · Advanced biosensing and bioanalysis techniques · Analytical Chemistry and Sensors
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References (18)
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