journal article·2007-05

Polycaprolactone biopolymer thin films obtained by matrix assisted pulsed laser evaporation

R. Cristescu, A. Doraiswamy, G. Socol, S. Grigorescu, E. Axente, D. Mihaiescu, A. Moldovan, R.J. Narayan, I. Stamatin, I.N. Mihailescu, B.J. Chisholm, D.B. Chrisey

Applied Surface Science· Volume 253· Issue 15
Publisher page

Abstract

Abstract We report the successful deposition of polycaprolactone polymer by MAPLE using a KrF* excimer laser ( λ = 248 nm, τ = 7 ns). According to FTIR spectra the deposited films have similar chemical structure to the dropcast material. The fluence plays a key role in optimizing the performances of MAPLE-synthesized polycaprolactone structures. We demonstrated that MAPLE allows for controlling the morphology of films to the level required in targeted drug delivery of pharmacologic agents.
Source: openaire · Quality: candidate unverified · Source record ↗

Research context

OpenAlex topics: Electrohydrodynamics and Fluid Dynamics · Diamond and Carbon-based Materials Research · Laser-Ablation Synthesis of Nanoparticles

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

References (11)

Show source-provided references
1. LaVan · Nat. Rev. Drug Discov. · 2002 · 1 · 7710.1038/nrd707 ↗
2. Brock Thomas · 2006 · 605
3. Lu · Adv. Drug Deliv. Rev. · 2004 · 56 · 162110.1016/j.addr.2004.05.002 ↗
4. Leoni · Adv. Drug Deliv. Rev. · 2004 · 56 · 21110.1016/j.addr.2003.08.014 ↗
5. Desai · Adv. Drug Deliv. Rev. · 2004 · 56 · 166110.1016/j.addr.2003.11.006 ↗
6. R.A. McGill, D.B. Chrisey, US Patent No. 6,025,036 (2000).
7. Cristescu · Thin Solid Films · 2004 · 453/454C · 26210.1016/j.tsf.2003.11.145 ↗
8. Cristescu · Appl. Surf. Sci. · 2006 · 252 · 464710.1016/j.apsusc.2005.07.152 ↗
9. Armani · J. Micromech. Microeng. · 2000 · 10 · 8010.1088/0960-1317/10/1/311 ↗
10. Magonov · 1996
11. Whangbo · Probe Microsc. · 1997 · 1 · 23