journal article·2024-11-05Open access

Advances in Graphene Field Effect Transistors (FETs) for Amine Neurotransmitter Sensing

Elmira Alimohammadzadeh, John Hedley

Applied Sciences· Volume 14· Issue 22

Abstract

Amine neurotransmitters (NTs) are crucial in the central nervous system, and dysregulation in their levels is implicated in a spectrum of neurological disorders. Thus, a precise and timely assessment of their concentrations is critical for early diagnosis and treatment efficacy monitoring. Graphene-based field effect transistors (GFETs) have become a ground-breaking instrument in the detection of these NTs because of their exceptional electrical characteristics and adaptability. This paper summarises the significant advancements in GFET biosensors in amine NT detection and highlights developments in the selectivity, sensitivity, and limit of detection (LOD) attained by selecting various graphene materials and functionalisation approaches.
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Research context

OpenAlex topics: Electrochemical sensors and biosensors · Graphene research and applications · Molecular Junctions and Nanostructures

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

School of Engineering, Newcastle University, Newcastle Upon Tyne NE1 7RU, UK

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