journal article·2025-03-01Open access

Two-dimensional (2D) materials for biomedical applications

Gengxin Wu, Brea B. Yang, Ying-Wei Yang

APL Materials· Volume 13· Issue 3

Abstract

Two-dimensional (2D) materials with unique structural and physicochemical properties have emerged as a powerful toolbox in biomedical applications. Nanoscale inorganic, organic, and hybrid 2D materials have shown exceptional potential in biosensing, drug delivery, tissue engineering, and cancer therapeutics. Their ultrahigh specific surface area, remarkable functionalization capabilities, and distinctive optoelectronic characteristics enable sophisticated interactions with biological systems. This Editorial covers the synthesis methods, characteristic properties, and emerging biomedical applications of 2D materials, with a particular focus on their potential in cancer theranostics and biosensing. It also highlights the critical challenges in clinical translation.
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Research context

OpenAlex topics: MXene and MAX Phase Materials · Graphene and Nanomaterials Applications · 2D Materials and Applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

College of Chemistry, Jilin University 1 , 2699 Qianjin Street, Changchun 130012,

New Trier High School 2 , 385 Winnetka Ave., Winnetka, Illinois 60093,

References (35)

Show source-provided references
1. Science · 2004 · 306 · 66610.1126/science.1102896 ↗
2. Nanoscale · 2012 · 4 · 383310.1039/c2nr31040f ↗
3. Chem. Rev. · 2020 · 120 · 1256310.1021/acs.chemrev.0c00505 ↗
4. Appl. Mater. Today · 2016 · 5 · 7310.1016/j.apmt.2016.09.012 ↗
5. Adv. Mater. · 2014 · 26 · 99210.1002/adma.201304138 ↗
6. Mater. Des. · 2021 · 198 · 10929810.1016/j.matdes.2020.109298 ↗
7. Nanomaterials · 2017 · 7 · 24610.3390/nano7090246 ↗
8. Chem. Mater. · 2023 · 35 · 835310.1021/acs.chemmater.3c02095 ↗
9. Chem. Soc. Rev. · 2018 · 47 · 626710.1039/c8cs00268a ↗
10. Adv. Mater. · 2015 · 27 · 726110.1002/adma.201502422 ↗
11. Chem. Soc. Rev. · 2021 · 50 · 61910.1039/D0CS00150C ↗
12. Mater. Today · 2021 · 50 · 27610.1016/j.mattod.2021.04.020 ↗
13. ACS Nano · 2015 · 9 · 945110.1021/acsnano.5b05040 ↗
14. ACS Appl. Bio Mater. · 2023 · 6 · 36510.1021/acsabm.2c00981 ↗
15. Prog. Solid State Chem. · 2024 · 74 · 10044310.1016/j.progsolidstchem.2024.100443 ↗
16. Chem. Sci. · 2023 · 14 · 526610.1039/d3sc00487b ↗
17. Small Methods · 2023 · 7 · 220158510.1002/smtd.202201585 ↗
18. Chem. Rev. · 2024 · 124 · 978510.1021/acs.chemrev.3c00851 ↗
19. Chem. Soc. Rev. · 2019 · 48 · 556410.1039/c8cs01003j ↗
20. J. Polym. Sci. · 2020 · 58 · 338710.1002/pol.20200584 ↗
21. Adv. Sci. · 2023 · 10 · 220388910.1002/advs.202203889 ↗
22. Adv. NanoBiomed Res. · 2024 · 4 · 230016310.1002/anbr.202300163 ↗
23. Chem. Rev. · 2021 · 121 · 375110.1021/acs.chemrev.0c01049 ↗
24. Small · 2024 · 20 · 230554810.1002/smll.202305548 ↗
25. J. Mater. Sci. · 2024 · 59 · 1072410.1007/s10853-024-09818-8 ↗
26. Nanoscale · 2017 · 9 · 676510.1039/c7nr00601b ↗
27. Bioact. Mater. · 2021 · 6 · 9110.1016/j.bioactmat.2020.07.014 ↗
28. Appl. Mater. Today · 2019 · 17 · 21610.1016/j.apmt.2019.08.005 ↗
29. J. Mater. Sci. · 2020 · 55 · 722610.1007/s10853-020-04507-8 ↗
30. J. Nanobiotechnol. · 2022 · 20 · 20710.1186/s12951-022-01395-9 ↗
31. Adv. Mater. · 2019 · 31 · 180587510.1002/adma.201805875 ↗
32. Adv. Funct. Mater. · 2022 · 32 · 220343010.1002/adfm.202203430 ↗
33. Mater. Horiz. · 2024 · 11 · 348210.1039/d4mh00068d ↗
34. Nanoscale Horiz. · 2018 · 3 · 7410.1039/c7nh00158d ↗
35. Chem. Rec. · 2024 · 24 · e20240001010.1002/tcr.202480401 ↗