Artificial tactile system for pressure monitoring in extracorporeal circulation processes

Current intraoperative pressure monitoring methods still face significant limitations in perception and feedback, struggling to strike a balance between precision and wearable flexibility. Inspired by biological skin, we propose a biomimetic tactile sensing system for pressure monitoring during extracorporeal circulation, comprising flexible pressure sensors and artificial synaptic transistors. Aimed at addressing the aforementioned issues, our system employs a pyramid-shaped elastic design for flexible pressure sensors, utilizing biocompatible materials polydimethylsiloxane and multi-walled carbon nanotubes as the strain-sensitive layer. This configuration boasts ultra-high sensitivity and resolution (115 kPa−1), accurately detecting subtle pressure changes, such as blood circulation wall pressures. With artificial synaptic transistors as the information processing core, our system successfully simulates crucial neural processing functions, including excitatory post-synaptic currents and double-pulse facilitation, while providing alerts for abnormal blood pressure signals. This system facilitates real-time data processing at the device edge, reducing power consumption, improving efficiency, and better addressing the demands of large-scale physiological pressure data processing. It presents a significant reference for future developments in biomedical electronics and bionics.