journal article·2025-08-01Open access

A novel perspective on denoising using quantum localization with application to medical imaging

Amirreza Hashemi, Sayantan Dutta, Bertrand Georgeot, Denis Kouamé, Hamid Sabet

AIP Advances· Volume 15· Issue 8

Abstract

Background noise in many fields, such as medical imaging, poses significant challenges for accurate diagnosis, prompting the development of denoising algorithms. Traditional methodologies, however, often struggle to address the complexities of noisy environments in high dimensional imaging systems. This paper introduces a novel quantum-inspired approach for image denoising, drawing upon principles of quantum and condensed matter physics. Our approach views medical images as amorphous structures akin to those found in condensed matter physics, and we propose an algorithm that incorporates the concept of mode resolved localization directly into the denoising process. Notably, unlike previous studies that considered localization as a hindrance, our approach considers quantum localization as a fundamental component of image reconstruction, which is used to differentiate between noisy and non-noisy modes based on diffusivity and localization measurements. This perspective eliminates the need for hyperparameter tuning, making the proposed method a standalone algorithm that can be implemented with minimal manual intervention and can perform automatic filtering of noise regardless of noise level. Through numerical validation, we showcase the effectiveness of our approach in addressing noise-related challenges in imaging, and especially medical imaging, underscoring its relevance for possible quantum computing applications.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Sparse and Compressive Sensing Techniques · Image and Signal Denoising Methods · Blind Source Separation Techniques

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Radiology, Massachusetts General Hospital and Harvard Medical School 1 , Boston, Massachusetts 02129,

Department of Radiology, Weill Cornell Medicine 2 , New York, Massachusetts 10065,

Advanced Technology Group, GE HealthCare 3 , Bangalore 560066,

France Laboratoire de Physique Théorique, Université de Toulouse, CNRS, UPS 4 , Toulouse 31042,

Université de Toulouse, CNRS, IRIT 5 , Toulouse 31042,

Funding

National Institute of Health · National Science Foundation · Association Nationale de la Recherche et de la Technologie

References (53)

Show source-provided references
1. A fractional integral method inverse distance weight-based for denoising depth images10.1063/5.0185438 ↗
2. Image enhancement using an improved adaptive contrast enhancement algorithm in neutron radiography10.1063/5.0157479 ↗
3. Research on hybrid segmentation technologies for postprocessing the lung and trachea CT images10.1063/5.0218772 ↗
4. Spatially guided nonlocal mean approach for denoising of PET images10.1002/mp.14024 ↗
5. Ultrasound image enhancement using structure oriented adversarial network10.1109/lsp.2018.2858147 ↗
6. Real-time image denoising of mixed Poisson–Gaussian noise in fluorescence microscopy images using ImageJ10.1364/optica.448287 ↗
7. A. Hashemi , Y.Feng, A.Rahmim, and H.Sabet, “Spherical CNN for medical imaging applications: Importance of equivariance in image reconstruction and denoising,” arXiv:2307.03298 (2023).
8. Some proximal methods for Poisson intensity CBCT and PET10.3934/ipi.2012.6.565 ↗
9. Locally weighted total variation denoising for ringing artifact suppression in PET reconstruction using PSF modeling
10. Locally weighted total variation denoising for ringing artifact suppression in PET reconstruction using PSF modeling
11. Novel Bayesian multiscale method for speckle removal in medical ultrasound images10.1109/42.938245 ↗
12. Ultrasound image despeckling using stochastic distance-based BM3D10.1109/tip.2017.2685339 ↗
13. Limited-angle TOF-PET for intraoperative surgical applications: Proof of concept and first experimental data10.1088/1748-0221/17/01/t01002 ↗
14. S. Sajedi , Y.Feng, and H.Sabet, “Limited-angle TOF-PET for intraoperative surgical applications: Simulation study,” arXiv:2402.06742 (2024).
15. Limited-angle computed tomography with deep image and physics priors10.1038/s41598-021-97226-2 ↗
16. An improved statistical iterative algorithm for sparse-view and limited-angle CT image reconstruction10.1038/s41598-017-11222-z ↗
17. Novel Compton SPECT camera for whole-body diagnostic and targeted radionuclide therapy applications
18. Multi-modal 3D imaging of radionuclides using multiple hybrid Compton cameras10.1038/s41598-022-06401-6 ↗
19. Simultaneous in vivo imaging with PET and SPECT tracers using a Compton-PET hybrid camera10.1038/s41598-021-97302-7 ↗
20. 2001
21. Quantum mechanics in computer vision: Automatic object extraction
22. A quantum mechanics-based framework for image processing and its application to image segmentation10.1007/s11128-015-1072-3 ↗
23. Quantum mechanics-based signal and image representation: Application to denoising10.1109/ojsp.2021.3067507 ↗
24. Despeckling ultrasound images using quantum many-body physics
25. Plug-and-play quantum adaptive denoiser for deconvolving Poisson noisy images10.1109/access.2021.3118608 ↗
26. Image denoising inspired by quantum many-body physics
27. An undulatory theory of the mechanics of atoms and molecules10.1103/physrev.28.1049 ↗
28. Diffusons, locons and propagons: Character of atomic vibrations in amorphous Si10.1080/014186399255836 ↗
29. Thermal conductivity and localization in glasses: Numerical study of a model of amorphous silicon10.1103/physrevb.48.12589 ↗
30. A method for distinguishing between propagons, diffusions, and locons10.1063/1.4955420 ↗
31. Effects of medium range order on propagon thermal conductivity in amorphous silicon10.1063/1.5124821 ↗
32. Non-crystalline, amorphous and liquid electronic semiconductors
33. Absence of diffusion in certain random lattices10.1103/physrev.109.1492 ↗
34. 1990
35. High-quality continuous random networks10.1103/physrevb.62.4985 ↗
36. Empirical interatomic potential for silicon with improved elastic properties10.1103/physrevb.38.9902 ↗
37. The general utility lattice program (GULP)10.1080/0892702031000104887 ↗
38. NISQ computing: Where are we and where do we go?10.1007/s43673-022-00058-z ↗
39. Is quantum advantage the right goal for quantum machine learning?10.1103/prxquantum.3.030101 ↗
40. H. Ammari , S.Barandun, and A.Uhlmann, “Subwavelength localisation in disordered systems,” arXiv:2412.13954 (2025).10.1098/rspa.2025.0407 ↗
41. Deep unfolding of image denoising by quantum interactive patches
42. A novel image denoising algorithm using concepts of quantum many-body theory10.1016/j.sigpro.2022.108690 ↗
43. Quantum algorithm for signal denoising10.1109/lsp.2023.3344071 ↗
44. DIVA: Deep unfolded network from quantum interactive patches for image restoration10.1016/j.patcog.2024.110676 ↗
45. Measurement of the parametrized single-photon response function of a large area picosecond photodetector for time-of-flight PET applications10.1109/trpms.2021.3065890 ↗
46. Concept design and Monte Carlo performance evaluation of HeadphonePET: A novel brain-dedicated PET system based on partial cylindrical detectors10.1088/1748-0221/13/07/p07008 ↗
47. Dynamic Cardiac SPECT for diagnostic and theranostics applications: Latest results
48. DB-SPECT, a fixed-gantry SPECT scanner for dynamic brain imaging: Design concept and first results
49. Application of artificial intelligence in PET instrumentation10.1016/j.cpet.2021.09.011 ↗
50. Light spread manipulation in scintillators using laser induced optical barriers10.1109/tns.2018.2809570 ↗
51. Development of crosshair light sharing PET detector with TOF and DOI capabilities using fast LGSO scintillator10.1088/1361-6560/ac2f8b ↗
52. A layered single-side readout depth of interaction time-of-flight-PET detector10.1088/1361-6560/abd592 ↗
53. Position estimation using neural networks in semi-monolithic PET detectors10.1088/1361-6560/aca389 ↗