A novel magnetic stimulation device with quasi-exponential stimulus currents
Source abstract
Abstract
Since its invention in 1985, the magnetic stimulator has been based on an oscillating circuit consisting of a capacitor and a coil. Depending on how the energy is switched, different pulse shapes are generated. These play an important role in the activation of nerves. While it is possible to generate nearly arbitrary pulse shapes, this freedom comes with complex and costly power electronics. We present a novel monophasic system that can generate extremely steep edges by inductive intermediate storage of pulse energy. It requires a very simple charging circuit, while the pulse amplitude and pulse duration are controlled by the switching times of two IGBTs. By varying these switching times with an input voltage of 140 VAC, our prototype generates pulses with a pulse length between 155 and 200 μs and a maximum stimulation coil current between 2.1 and 2.8 kA. The total energy in the system (depending on the input voltage and switching time) is limited by exceeding the dielectric strength of the IGBTs due to voltage peaks that occur during switching. These peaks were counteracted to a certain extent using RCD snubbers. Our design enables the development of low-cost and compact monophasic magnetic stimulators and, with its novel topology, opens up further possibilities in generating monophasic pulse shapes.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Transcranial Magnetic Stimulation Studies · Neuroscience and Neural Engineering · Advanced Sensor and Energy Harvesting Materials
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Munich Institute of Biomedical Engineering (MIBE), Technical University of Munich , Garching 85748,
Funding
Bayerisches Staatsministerium für Wirtschaft und Medien, Energie und Technologie
References (15)
Show source-provided references
1. Transcranial magnetic stimulation: A review of its evolution and current applications10.4103/ipj.ipj_88_18 ↗
2. Enhancement of neuromodulation with novel pulse shapes generated by controllable pulse parameter transcranial magnetic stimulation10.1016/j.brs.2015.08.013 ↗
3. TMS of primary motor cortex with a biphasic pulse activates two independent sets of excitable neurones10.1016/j.brs.2018.01.001 ↗
4. Non-invasive electrical and magnetic stimulation of the brain, spinal cord, roots and peripheral nerves: Basic principles and procedures for routine clinical and research application. An updated report from an I.F.C.N. committee10.1016/j.clinph.2015.02.001 ↗
5. The role of pulse shape in motor cortex transcranial magnetic stimulation using full-sine stimuli10.1371/journal.pone.0115247 ↗
6. A transcranial magnetic stimulator inducing near-rectangular pulses with controllable pulse width (cTMS)10.1109/tbme.2007.900540 ↗
7. Repetitive transcranial magnetic stimulator with controllable pulse parameters10.1088/1741-2560/8/3/036016 ↗
8. Controllable pulse parameter transcranial magnetic stimulator with enhanced circuit topology and pulse shaping10.1088/1741-2560/11/5/056023 ↗
9. flexTMS–a novel repetitive transcranial magnetic stimulation device with freely programmable stimulus currents10.1109/tbme.2012.2195180 ↗
10. Modular multilevel TMS device with wide output range and ultrabrief pulse capability for sound reduction10.1088/1741-2552/ac572c ↗
11. Modular pulse synthesizer for transcranial magnetic stimulation with flexible user-defined pulse shaping and rapidly changing pulses in sequences10.1088/1741-2552/ac9d65 ↗
12. Switching voltage transient protection schemes for high-current IGBT modules10.1109/28.649974 ↗
13. Snubber considerations for IGBT applications
14. Design and fabrication of low-loss toroidal air-core inductors
15. Optimal pulse configuration for peripheral inductive nerve stimulation10.1088/2057-1976/ac52d8 ↗