Some observations on the mechanics and dynamics of tumor heterogeneity

The genetic, proteomic and cytostructural complexities of malignant neoplasms have received much attention in cancer research for many years. However, studies of the mechanics of neoplastic phenomena at the meso- and macroscales are also now providing opportunities for understanding some aspects of tumor growth and developing new therapeutic possibilities. We provide a brief overview of some of the recent work in these areas, with emphasis on physical considerations of certain aspects of the mechanics and fluid dynamics of tumor cell invasion and dispersion.