Multifunctional platform for photothermal therapy combined with luminescence nanothermometry probes
Source abstract
Abstract
The design of multifunctional magnetic nanoparticles (NPs) that can generate and monitor heat release in real-time during thermal therapy is a major challenge in nanomedicine. In this work, a trimodal system that combines magnetic hyperthermia (MH), photothermal therapy (PT) and luminescence nano-thermometry (LT) has been set up in a single platform. Magnetite NPs were optimized focusing on MH and PT; then, the NPs have been coated with embedded Nd3+ cations to enhance the PT and to act as LT probe. Nd3+ is an interesting luminescent probe, with excitation around 800 nm and emission at the second biological window. Such hybrid system could act as heat mediator and imaging probe for in situ thermometer during the PT and MH, since these wavelengths belong to the biological windows.
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Research context
OpenAlex topics: Photoacoustic and Ultrasonic Imaging · Nanoplatforms for cancer theranostics · Gas Sensing Nanomaterials and Sensors
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Instituto de Magnetismo Aplicado (UCM-ADIF) 1 , A6 km. 22.500, 28230 Las Rozas, Spain
Dpto. de Óptica, Facultad de Ciencias Físicas, Universidad Complutense de Madrid 2 , Plaza de las Ciencias 1, 28040 Madrid, Spain
Funding
Ministerio de Ciencia e Inovação · Comunidad de Madrid · Consejería de Educación, Juventud y Deporte, Comunidad de Madrid
References (17)
Show source-provided references
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