Graphene-assisted titanium dioxide Z-mechanism photoelectrode as enzymatic glucose biosensor
Source abstract
Abstract
Highly exposed surfaces of anatase TiO2 crystals are of interest due to their excellent photogenerated electron–hole pair separation effect and high photocatalytic activity. In this work, a Z-mechanism biosensor with reduced graphene oxide (rGO) and anatase TiO2 nanocrystals combined with PDA (TiO2/rGO/PDA) was successfully synthesized. rGO was combined with the co-exposed (001) and (101) facets of TiO2 nanocrystals to construct a Z-mechanism in which rGO acts as an electron transport medium and provides a channel for the transfer of electrons, resulting in TiO2 nanocrystals with high photoelectron–hole pair separation efficiency and strong redox ability. The coated PDA polymer not only could absorb visible light but also has good stability and biocompatibility, which helps to increase the adsorption of target enzyme molecules. The TiO2/rGO/PDA/GOx biosensor with the Z-mechanism displays the sensitivity of 13.82 μA mM−1 cm−2 in 0.1M PBS solution (pH = 7.4) with a linear range of 0–3 mM and the LOD of 0.034 µM. In general, the application of the Z-mechanism in biosensors would provide a new orientation for the design of biosensors.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Advanced biosensing and bioanalysis techniques · Electrochemical sensors and biosensors · Advanced Nanomaterials in Catalysis
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
State Key Laboratory of Marine Resource Utilization in South China Sea, College of Materials Science and Engineering, Hainan University 1 , Haikou 570228, China
Department of Clinical Laboratory, The First Affiliated Hospital of Hainan Medical University 2 , Haikou 570102, China
Department of Clinical Laboratory of the Second Affiliated Hospital, School of Tropical Medicine, Key Laboratory of Emergency and Trauma of Ministry of Education, Research Unit of Island Emergency Medicine, Chinese Academy of Medical Sciences (No. 2019RU013), Hainan Medical University 3 , Haikou 571199, China
Funding
The National Natural Science Foundation of China
References (42)
Show source-provided references
1. Truly immobilization-free diffusivity-mediated photoelectrochemical biosensing strategy for facile and highly sensitive MicroRNA assay10.1021/acs.analchem.8b02523 ↗
2. Enhanced visible-light photoelectrochemical performance via chemical vapor deposition of Fe2O3 on a WO3 film to form a heterojunction10.1007/s12598-019-01311-5 ↗
3. {001}/{101} facets co-exposed TiO2 microsheet arrays with lanthanum doping for enhancing photocatalytic CO2 reduction10.1007/s10854-020-04479-0 ↗
4. Nucleic acid-functionalized metal-organic framework-based homogeneous electrochemical biosensor for simultaneous detection of multiple tumor biomarkers10.1021/acs.analchem.8b05599 ↗
5. Donor–acceptor compensated ZnO semiconductor for photoelectrochemical biosensors10.1021/acsami.1c07499 ↗
6. Core/shell structured CdS/polydopamine/TiO2 ternary hybrids as highly active visible-light photocatalysis10.1016/j.jcis.2019.02.080 ↗
7. Fabrication of BiOBr nanosheets@TiO2 nanobelts p–n junction photocatalysts for enhanced visible-light activity10.1016/j.apsusc.2015.12.249 ↗
8. Constructing TiO2 p-n homojunction for photoelectrochemical and photocatalytic hydrogen generation10.1016/j.nanoen.2016.08.054 ↗
9. Single-crystal TiO2/SrTiO3 core–shell heterostructured nanowire arrays for enhanced photoelectrochemical performance10.1007/s12598-019-01221-6 ↗
10. Highly active TiO2/g-C3N4/G photocatalyst with extended spectral response towards selective reduction of nitrobenzene10.1016/j.apcatb.2016.10.003 ↗
11. Anatase TiO2 nanocrystals with exposed {001} facets on graphene sheets via molecular grafting for enhanced photocatalytic activity10.1039/c1nr11411e ↗
12. Self-assembly of nitrogen-doped TiO2 with exposed {001} facets on a graphene scaffold as photo-active hybrid nanostructures for reduction of carbon dioxide to methane10.1007/s12274-014-0514-z ↗
13. Ag2O/TiO2 hollow microsphere heterostructures with exposed high-energy {001} crystal facets and high photocatalytic activities10.1007/s10854-020-03697-w ↗
14. TiO2 films with oriented anatase {001} facets and their photoelectrochemical behavior as CdS nanoparticle sensitized photoanodes10.1039/c0jm02694h ↗
15. Photoelectrochemical glucose biosensor based on the heterogeneous facets of nanocrystalline TiO2/Au/glucose oxidase films10.1021/acsanm.0c00086 ↗
16. Z-scheme heterojunction g-C3N4@PDA/BiOBr with biomimetic polydopamine as electron transfer mediators for enhanced visible-light driven degradation of sulfamethoxazole10.1016/j.cej.2020.124014 ↗
17. Efficient Z-scheme photocatalysts of ultrathin g-C3N4-wrapped Au/TiO2-nanocrystals for enhanced visible-light-driven conversion of CO2 with H2O10.1016/j.apcatb.2019.118314 ↗
18. One-step electrodeposition of high-quality amorphous molybdenum sulfide/RGO photoanode for visible-light sensitive photoelectrochemical biosensing10.1016/j.snb.2018.03.117 ↗
19. Multifunctional superelastic, superhydrophilic, and ultralight nanocellulose-based composite carbon aerogels for compressive supercapacitor and strain sensor10.1002/adfm.202113082 ↗
20. Enhanced catalytic performance of graphene-TiO2 nanocomposites for synergetic degradation of fluoroquinolone antibiotic in pulsed discharge plasma system10.1016/j.apcatb.2019.01.052 ↗
21. Hydrothermal etching fabrication of TiO2@graphene hollow structures: Mutually independent exposed {001} and {101} facets nanocrystals and its synergistic photocaltalytic effects10.1038/srep33839 ↗
22. Ag-decorated 3D flower-like Bi2MoO6/rGO with boosted photocatalytic performance for removal of organic pollutants10.1007/s12598-020-01574-3 ↗
23. Immobilization of Pt nanoparticles via rapid and reusable electropolymerization of dopamine on TiO2 nanotube arrays for reversible SERS substrates and nonenzymatic glucose sensors10.1002/smll.201604240 ↗
24. Polydopamine-assisted decoration of TiO2 nanotube arrays with enzyme to construct a novel photoelectrochemical sensing platform10.1016/j.snb.2017.06.168 ↗
25. True photoreactivity origin of Ti(3+)-doped anatase TiO2 crystals with respectively dominated exposed {001}, {101}, and {100} facets10.1021/acsomega.9b01648 ↗
26. Enhanced photocatalytic CO(2)-reduction activity of anatase TiO(2) by coexposed {001} and {101} facets10.1021/ja5044787 ↗
27. Anatase TiO2 with co-exposed (001) and (101) surface-based photocatalytic materials for energy conversion and environmental purification10.1002/asia.202001085 ↗
28. Constructing a TiO2/PDA core/shell nanorod array electrode as a highly sensitive and stable photoelectrochemical glucose biosensor10.1039/c9ra10445c ↗
29. Hollow anatase TiO2 single crystals and mesocrystals with dominant {101} facets for improved photocatalysis activity and tuned reaction preference10.1021/cs300229e ↗
30. Nanosized anatase TiO2 single crystals with tunable exposed (001) facets for enhanced energy conversion efficiency of dye-sensitized solar cells10.1002/adfm.201100828 ↗
31. Competitive adsorption of dopamine and rhodamine 6G on the surface of graphene oxide10.1021/am404881p ↗
32. Synthesis, characterization and enhanced photocatalytic CO2 reduction activity of graphene supported TiO2 nanocrystals with coexposed {001} and {101} facets10.1039/c5cp07854g ↗
33. Tuning PbS QDs deposited onto TiO2 nanotube arrays to improve photoelectrochemical performances10.1016/j.jcis.2016.09.002 ↗
34. Enhanced charge-carrier transfer by CdS and Ag2S quantum dots co-sensitization for TiO2 nanotube arrays10.1016/j.jcis.2015.06.038 ↗
35. Facile synthesis of anatase TiO(2) quantum-dot/graphene-nanosheet composites with enhanced electrochemical performance for lithium-ion batteries10.1002/adma.201304338 ↗
36. Fabrication of n-type CuInS2 modified TiO2 nanotube arrays heterostructure photoelectrode with enhanced photoelectrocatalytic properties10.1016/j.apcatb.2014.03.035 ↗
37. Enhanced photoelectrochemical water splitting with TiO2@Ag2O nanowire arrays via p-n heterojunction formation10.1016/j.solmat.2017.08.033 ↗
38. Glucose photoelectrochemical enzyme sensor based on competitive reaction of ascorbic acid10.1016/j.bios.2020.112466 ↗
39. A self-powered photoelectrochemical glucose biosensor based on supercapacitor Co3O4-CNT hybrid on TiO210.1016/j.bios.2018.07.049 ↗
40. BaTiO3 nanoparticles as biomaterial film for self-powered glucose sensor application10.1016/j.snb.2016.05.004 ↗
41. Nanoflake-like SnS(2) matrix for glucose biosensing based on direct electrochemistry of glucose oxidase10.1016/j.bios.2011.04.031 ↗
42. Electrochemiluminescent immunosensor based on CdS quantum dots for ultrasensitive detection of microcystin-LR10.1016/j.snb.2015.03.019 ↗