Preparation and mechanical performance analysis of porous Ti6Al4V scaffold fabricated by direct ink writing
Source abstract
Abstract
In order to mitigate the stress-shielding effect resulting from the stiffness disparity between titanium alloy and bone, the use of additive manufacturing to create porous Ti6Al4V components shows promise for orthopedic implant applications. In this study, a novel hot-melt–quick-frozen polyvinyl alcohol hydrogel was developed for direct ink writing to create porous titanium structures using Ti6Al4V powders with an irregular morphology. The rheological and sintering properties of inks with varying solid phase contents were examined to assess their molding quality. Furthermore, the effect of porosity on the morphology, shrinkage, and mechanical properties of the scaffolds was thoroughly investigated. The results of the experiments show that inks loaded with 65 vol. % Ti6Al4V particles exhibit the highest printing performance. Furthermore, the analysis revealed a positive correlation between the total porosity of the scaffold and its mechanical performance. In particular, the strength of the scaffold with a porosity of 54.8% exceeded that of human bone, and it also exhibited matched stiffness. Upon analyzing the final microstructure and mechanical properties, it is evident that these scaffolds meet the necessary criteria for use as orthopedic implants.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Additive Manufacturing and 3D Printing Technologies · Additive Manufacturing Materials and Processes · Titanium Alloys Microstructure and Properties
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Materials Engineering, Hebei Vocational University of Industry and Technology , Shijiazhuang 050019, China
Funding
Science and Technology Project of Hebei Education Department · The Key Research and Development Program of Hebei
References (44)
Show source-provided references
1. Topological design and additive manufacturing of porous metals for bone scaffolds and orthopaedic implants: A review10.1016/j.biomaterials.2016.01.012 ↗
2. Ti based biomaterials, the ultimate choice for orthopaedic implants—A review10.1016/j.pmatsci.2008.06.004 ↗
3. Composition optimization of low modulus and high-strength TiNb-based alloys for biomedical applications10.1016/j.jmbbm.2016.10.013 ↗
4. Recent advances in the design of titanium alloys for orthopedic applications10.1586/17434440.2.6.741 ↗
5. Strength properties of a porous titanium alloy Ti6Al4V with diamond structure obtained by laser power bed fusion (LPBF)10.3390/ma13225138 ↗
6. Effect of pore size on bone ingrowth into porous titanium implants fabricated by additive manufacturing: An in vivo experiment10.1016/j.msec.2015.10.069 ↗
7. Titanium foam through powder metallurgy route using acicular urea particles as space holder10.1016/j.matlet.2011.07.004 ↗
8. Mechanical properties of directionally freeze-cast titanium foams10.1016/j.actamat.2010.09.019 ↗
9. Ovalbumin as foaming agent for Ti6Al4V foams produced by gelcasting10.1016/j.jallcom.2016.06.218 ↗
10. Additively manufactured scaffolds for bone tissue engineering and the prediction of their mechanical behavior: A review10.3390/ma10010050 ↗
11. A review of powder additive manufacturing processes for metallic biomaterials10.1016/j.powtec.2017.12.058 ↗
12. Additive manufacturing of metallic components—Process, structure and properties10.1016/j.pmatsci.2017.10.001 ↗
13. Morphology and surface topography of Ti6Al4V lattice structure fabricated by selective laser sintering10.1515/bpasts-2017-0011 ↗
14. Manufacturing and characterization of Ti6Al4V lattice components manufactured by selective laser melting10.3390/ma7064803 ↗
15. Electron beam melted scaffolds for orthopedic applications10.1016/j.addma.2017.08.005 ↗
16. Defect Formation mechanisms in selective laser melting: A review10.1007/s10033-017-0121-5 ↗
17. Additive manufacturing of titanium alloys in the biomedical field: Processes, properties and applications10.5301/jabfm.5000371 ↗
18. Direct ink writing of geopolymeric inks10.1016/j.jeurceramsoc.2017.01.030 ↗
19. A biocompatible thermoset polymer binder for Direct Ink Writing of porous titanium scaffolds for bone tissue engineering10.1016/j.msec.2018.10.033 ↗
20. In vitro and in vivo study of titanium grade IV and titanium grade V implants with different surface treatments10.3390/met10040449 ↗
21. Direct ink writing of a preceramic polymer and fillers to produce hardystonite (Ca2ZnSi2O7) bioceramic scaffolds10.1111/jace.14213 ↗
22. Ti/β-TCP composite porous scaffolds fabricated by direct ink writing10.1080/17452759.2023.2192703 ↗
23. Direct ink writing of porous Ti6Al4V alloys via UV light curing10.1002/adem.202200176 ↗
24. Direct ink writing of porous Fe–Ti6Al4V and Fe–Inconel 718 bimetallic structures10.1016/j.jmrt.2023.07.103 ↗
25. Titanium scaffolds by direct ink writing: Fabrication and functionalization to guide osteoblast behavior10.3390/met10091156 ↗
26. Direct ink writing of porous titanium (Ti6Al4V) lattice structures10.1016/j.msec.2019.109794 ↗
27. Robocasting of structural ceramic parts with hydrogel inks10.1016/j.jeurceramsoc.2016.03.001 ↗
28. Pluronic F127 hydrogel characterization and biofabrication in cellularized constructs for tissue engineering applications10.1016/j.procir.2015.11.001 ↗
29. 3D printing of open-porous cellular ceramics with high specific strength10.1016/j.jeurceramsoc.2017.06.001 ↗
30. 3D-printing of lightweight cellular composites10.1002/adma.201401804 ↗
31. Linking rheology and printability for dense and strong ceramics by direct ink writing10.1038/s41598-017-06115-0 ↗
32. Direct-ink writing of strong and biocompatible titanium scaffolds with bimodal interconnected porosity10.1016/j.addma.2021.101859 ↗
33. Mechanical characterization of Al2O3 twisted honeycomb structures fabricated by digital light processing 3D printing10.1016/j.ceramint.2023.06.232 ↗
34. Fabrication of soft tissue engineering scaffolds by means of rapid prototyping techniques10.1023/a:1016189724389 ↗
35. Fabrication and characterization of porous Ti6Al4V parts for biomedical applications using electron beam melting process10.1016/j.matlet.2008.10.065 ↗
36. 3D printing of metal-organic framework incorporated porous scaffolds to promote osteogenic differentiation and bone regeneration10.1039/d0nr06297a ↗
37. Pressureless sintering of titanium and titanium alloys: Sintering densification and solute homogenization10.1016/b978-0-12-800054-0.00012-5 ↗
38. Multiscale osteointegration as a new paradigm for the design of calcium phosphate scaffolds for bone regeneration10.1016/j.biomaterials.2010.01.052 ↗
39. Mechanical properties and biocompatibility of porous titanium scaffolds for bone tissue engineering10.1016/j.jmbbm.2017.07.015 ↗
40. Nano calcium-deficient hydroxyapatite/O-carboxymethyl chitosan-CaCl2 microspheres loaded with Rhein for bone defect repair10.1007/s42235-022-00179-z ↗
41. Solid freeform fabrication of three-dimensional scaffolds for engineering replacement tissues and organs10.1016/s0142-9612(03)00030-9 ↗
42. The effect of strut size on microstructure and compressive strength of porous Ti6Al4V lattices printed via direct ink writing10.1016/j.msea.2020.139484 ↗
43. Microstructure and mechanical behavior of porous Ti–6Al–4V parts obtained by selective laser melting10.1016/j.jmbbm.2013.05.011 ↗
44. 1999