Functional helicoidal model of DNA molecule with elastic nonlinearity
Source abstract
Abstract
We constructed a functional DNA molecule model on the basis of a flexible helicoidal sensor, specifically, a pretwisted hollow nano-strip. We study in this article the helicoidal nano- sensor model with a pretwisted strip axial extension corresponding to the overstretching transition of DNA from dsDNA to ssDNA. Our model and the DNA molecule have similar geometrical and nonlinear mechanical features unlike models based on an elastic rod, accordion bellows, or an imaginary combination of “multiple soft and hard linear springs”, presented in some recent publications.
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Research context
OpenAlex topics: Advanced biosensing and bioanalysis techniques · RNA Interference and Gene Delivery · DNA and Nucleic Acid Chemistry
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Affiliations
International Society of Automation (ISA) , 20 Randall St., Apt. 5G, Providence, Rhode Island 02904, USA
References (8)
Show source-provided references
1. An effective model of DNA like helicoidal structure: with length fluctuation nonlinearity10.1063/1.3574876 ↗
2. Flexible Helicoids, Atomic Force microscopy (AFM) Cantilevers in High mode Vibration, and Concave Notch hinges in Precision Measurements and Research10.3390/mi3020480 ↗
3. Single-molecule study of DNA mechanics10.1016/S0959-440X(00)00085-3 ↗
4. Salt dependence of the elasticity and overstretching transition single DNA molecules10.1016/S0006-3495(02)75658-0 ↗
5. Analysis of accordion DNA stretching revealed by the gold cluster ruler10.1103/PhysRevE.80.010901 ↗
6. DNA elastic nonlinearities as multiple smooth combinations of soft and hard springs10.1002/zamm.201200093 ↗
7. 2006
8. A. V. Tkachenko, “Elasticity of strongly stretched ssDNA,” arXiv:q-bio/0703027v1 [q-bio.BM](12 Mar 2007).10.1016/j.physa.2007.04.119 ↗