Non-enzymatic electrochemical sensor based on ZnO nanoparticles/porous graphene for the detection of hypoxanthine in pork meat
Source abstract
Abstract
In this study, we developed a pioneering non-enzymatic electrochemical sensor utilizing a flexible porous graphene electrode modified with ZnO nanoparticles (ZnO/fPGE sensor) to assess hypoxanthine (HXA) content in pork at post-mortem time. The ZnO/fPGE sensor was synthesized via hydrothermal method and direct laser writing with a CO2 laser on a polyimide film at ambient conditions. Its characterization was analyzed by Raman, Fourier-transform infrared spectroscopy, field-emission scanning microscopy, energy-dispersive x-ray spectroscopy, and cyclic voltammetric techniques. Linear response, the limit of detection, and sensitivity to the HXA were enhanced with the values of the range from 1.5 to 150, 0.14 µM, and 6.6 µA μM−1 cm−2, respectively. Effective resistance to common physiological interferences (such as uric acid, ascorbic acid, dopamine, glucose, and xanthine) was indicated, and additionally, the determination of HXA concentration in real samples with good selectivity is attributed to the synergistic effects between ZnO nanoparticles and fPGE. Therefore, the ZnO/fPGE has provided a favorable electrical environment for developing high-performance electrochemical biosensors to determine hypoxanthine in pork meat.
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Research context
OpenAlex topics: Electrochemical sensors and biosensors · Electrochemical Analysis and Applications · Analytical Chemistry and Sensors
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Institute of Materials Science, Vietnam Academy of Science and Technology 1 , 18 Hoang Quoc Viet, Cau Giay, Hanoi, Vietnam
Graduate University of Science and Technology, Vietnam Academy of Science and Technology 2 , 18 Hoang Quoc Viet, Cau Giay, Hanoi, Vietnam
Faculty of Chemistry, VNU University of Science 3 , 19 Le Thanh Tong, Hoan Kiem, Hanoi, VietNam
University of Science and Technology of Hanoi, Vietnam Academy of Science and Technology 4 , 18 Hoang Quoc Viet, Cau Giay, Hanoi, Vietnam
Kotelnikov Institute of Radioengineering and Electronics of the Russian Academy of Sciences 5 , Moscow, Russian Federation
Hanoi University of Science and Technology 6 , 1 Dai Co Viet, Hai Ba Trung, Hanoi, Vietnam
Funding
Vietnam Ministry of Science and Technology · Nanowire manipulation-RSF
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