journal article·2019-12-01Open access

Shape-controlled MnO nanoparticles as T1 MRI contrast agents

A. Banerjee, W. Zeng, M. Taheri, B. Blasiak, B. Tomanek, S. Trudel

AIP Advances· Volume 9· Issue 12

Abstract

Magnetic resonance imaging is a non-invasive imaging method that offers high-resolution, high quality in vivo visualization for medical diagnostics. Magnetic nanoparticles (NPs) containing Mn2+ offer an attractive alternative to Gd-based molecular contrast agents for T1 MRI. In this work, we show that highly anisotropic MnO NPs can be generated from a single precursor using simple synthetic protocols. These anisotropic morphologies offer better contrast augmentation when compared to spherical MnO NPs of similar sizes.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Lanthanide and Transition Metal Complexes · Characterization and Applications of Magnetic Nanoparticles · Nanoparticle-Based Drug Delivery

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Chemistry and Institute for Quantum Science and Technology, University of Calgary 1 , 2500 University Dr. NW, Calgary, Alberta T2N 1N4, Canada

Department of Clinical Neurosciences, University of Calgary 2 , 3330 Hospital Dr. NW, Calgary, Alberta T2N 4N1, Canada and , 152 Radzikowskiego, Krakow 31-342, Poland

Institute of Nuclear Physics, Polish Academy of Sciences 2 , 3330 Hospital Dr. NW, Calgary, Alberta T2N 4N1, Canada and , 152 Radzikowskiego, Krakow 31-342, Poland

Department of Oncology, University of Alberta, Cross Cancer Institute 3 , 11560 University Avenue, Edmonton, Alberta T6G 1Z2, Canada

Funding

Natural Sciences and Engineering Research Council of Canada · Alberta Innovates - Health Solutions · Canada Foundation for Innovation · University of Calgary

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