journal article·2017-05-01Open access

Towards a magnetoresistive platform for neural signal recording

P. P. Sharma, G. Gervasoni, E. Albisetti, F. D’Ercoli, M. Monticelli, D. Moretti, N. Forte, A. Rocchi, G. Ferrari, P. Baldelli, M. Sampietro, F. Benfenati, R. Bertacco, D. Petti

AIP Advances· Volume 7· Issue 5

Abstract

A promising strategy to get deeper insight on brain functionalities relies on the investigation of neural activities at the cellular and sub-cellular level. In this framework, methods for recording neuron electrical activity have gained interest over the years. Main technological challenges are associated to finding highly sensitive detection schemes, providing considerable spatial and temporal resolution. Moreover, the possibility to perform non-invasive assays would constitute a noteworthy benefit. In this work, we present a magnetoresistive platform for the detection of the action potential propagation in neural cells. Such platform allows, in perspective, the in vitro recording of neural signals arising from single neurons, neural networks and brain slices.
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Research context

OpenAlex topics: Neural dynamics and brain function · Neuroscience and Neural Engineering · Advanced Memory and Neural Computing

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Politecnico di Milano 1 Department of Physics, , Milan 20133, Italy

Politecnico di Milano 2 Department of Electronics, Information and Bioengineering, , Milan 20133, Italy

Italian Institute of Technology 3 Center of Synaptic Neuroscience, , Genova 16132, Italy

Funding

Fondazione Cariplo

References (31)

Show source-provided references
1. Eur. J. Physiol. · 1981 · 391 · 8510.1007/BF00656997 ↗
2. Nat. Rev. · 2012 · 13 · 40710.1038/nrn3241 ↗
3. Eur. J. Physiol. · 1990 · 490
4. Biosens. Bioelectron. · 2004 · 20 · 35810.1016/j.bios.2004.02.006 ↗
5. Biosens. Bioelectron. · 2005 · 21 · 16710.1016/j.bios.2004.08.011 ↗
6. J. Neurosci. · 1999 · 19 · 676710.1523/JNEUROSCI.19-16-06767.1999 ↗
7. J. Neurosci. Methods · 2012 · 203 · 40710.1016/j.jneumeth.2011.10.014 ↗
8. Nat. Nanotechnol. · 2011 · 7 · 17410.1038/nnano.2011.223 ↗
9. Nat. Nanotechnol. · 2012 · 7 · 18010.1038/nnano.2011.249 ↗
10. Nat. Nanotechnol. · 2012 · 7 · 18510.1038/nnano.2012.8 ↗
11. Nat. Nano. · 2012 · 7 · 14310.1038/nnano.2012.22 ↗
12. Nature · 2013 · 49910.1038/nature12354 ↗
13. Nat. Methods · 2009 · 610.1038/nmeth.1398 ↗
14. J. F. Barry, M. J. Turner, J. M. Schloss, D. R. Glenn, Y. Song, M. D. Lukin, H. Park, and R. L. Walsworth, arXiv:1602.01056 [Cond-Mat, Physics:physics, Physics:quant-Ph, Q-Bio] (2016).
15. Nat Commun · 2014 · 5 · 314110.1038/ncomms4141 ↗
16. J. PhysicsCondensed Matter · 2007 · 19 · 16522110.1088/0953-8984/19/16/165221 ↗
17. Sensors Actuators B Chem. · 2016
18. Appl. Phys. Lett. · 2011 · 98 · 7370210.1063/1.3554374 ↗
19. J. Appl. Phys. · 2011 · 109 · 07B30810.1063/1.3562915 ↗
20. Biosens. Bioelectron. · 2013 · 47 · 21310.1016/j.bios.2013.03.016 ↗
21. Sensors Actuators B Chem. · 2014 · 200 · 3910.1016/j.snb.2014.04.055 ↗
22. J. Phys. D. Appl. Phys. · 2007 · 40 · R33710.1088/0022-3727/40/21/R01 ↗
23. Sensors · 2016 · 1610.3390/s16071030 ↗
24. J. Appl. Phys. · 2008 · 103 · 07A91010.1063/1.2838626 ↗
25. Bioelectromagnetics · 2013 · 57810.1002/bem.21805 ↗
26. Front. Neural Circuits · 2012 · 6 · 110.3389/fncir.2012.00080 ↗
27. Rev. Sci. Instrum. · 1999 · 70 · 252010.1063/1.1149785 ↗
28. Current · 2008 · 44 · 2551
29. Magn. IEEE … · 2013 · 49 · 351210.1109/TMAG.2013.2239274 ↗
30. J. Appl. Phys. · 2005 · 97 · 910.1063/1.1861375 ↗
31. Micromachines · 2016 · 7 · 8810.3390/mi7050088 ↗