journal article·2020-02-01Open access

Immediate intervention effect of dielectric barrier discharge on acute inflammation in rabbit’s ear wound

Chengbiao Ding, Pengpeng Huang, Linfei Feng, Tao Jin, Yun Zhou, Yuanyuan He, Zhengwei Wu, Yi Liu

AIP Advances· Volume 10· Issue 2

Abstract

Acute inflammation is an anti-injury stress response which is beneficial to the human body. However, if the duration of acute inflammation is prolonged in specific people, such as critically ill patients and people with low resistance, it will worsen the disease and increase complication rates. Most medical researchers are committed to finding an effective method to shorten the duration of acute inflammation. The purpose of our work is to shorten the duration of acute inflammation in a rabbit’s ear wound by dielectric barrier discharge (DBD) low temperature plasma. The distribution and quantity of inflammatory cells in the rabbit’s ear wound treated by plasma were studied and calculated by using a high power optical microscope and Image J software. The reactive species of plasma were characterized by optical emission spectroscopy. The results showed that the number of inflammatory cells decreased from 2312.17 ± 242.52 to 880.17 ± 89.08 after plasma treatment for 3 min. In addition, plasma has a coagulation effect on the rabbit’s ear wound. Our results indicated that DBD low temperature plasma could be an effective tool to decrease the inflammatory response time and the inflammation was further alleviated with increased treatment time.
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Research context

OpenAlex topics: Plasma Applications and Diagnostics · Planarian Biology and Electrostimulation · Burn Injury Management and Outcomes

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Rehabilitation Medicine, The Second Hospital of Anhui Medical University 1 , Hefei, Anhui 230001, China

Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Anhui Medical University 2 , Hefei, Anhui 230001, China

School of Food and Biological Engineering, Hefei University of Technology 3 , Hefei 230009, China

Department of Geriatrics, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China 4 , Hefei, Anhui 230001, China

Department of Engineering and Applied Physics, University of Science and Technology of China 5 , Jinzhai Road 96, Hefei, Anhui 230026, China

Funding

University of Science and Technology of China · Anhui Science and Technology Department

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