journal article·2012-03-01Open access

Physics of cancer propagation: A game theory perspective

Chris Cleveland, David Liao, Robert Austin

AIP Advances· Volume 2· Issue 1

Abstract

This is a theoretical paper which examines at a game theoretical perspective the dynamics of cooperators and cheater cells under metabolic stress conditions and high spatial heterogeneity. Although the ultimate aim of this work is to understand the dynamics of cancer tumor evolution under stress, we use a simple bacterial model to gain fundamental insights into the progression of resistance to drugs under high competition and stress conditions.
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Research context

OpenAlex topics: Evolution and Genetic Dynamics · Evolutionary Game Theory and Cooperation · Mathematical Biology Tumor Growth

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Affiliations

Princeton University 1 Department of Physics, , Princeton, New Jersey 08544, USA

University of California San Francisco 2 Department of Pathology, , California 94143, USA

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