Mechanism of protofibril formation in aqueous collagen solutions
Source abstract
Abstract
The shear viscosity of aqueous collagen solutions was experimentally investigated over the temperature range of 303–353 K and collagen concentrations of 1–7 wt. %. A structural phase transition was observed at ∼315 K, corresponding to the onset of protofibril formation. It is shown that below this temperature, protofibrils containing both ordered and disordered segments are formed, with the proportion of ordered segments increasing as the temperature decreases, reaching ∼30% at 303 K. An analysis of the temperature dependence of the order parameter for the structural transition in the water–collagen system suggests that this transition exhibits characteristics of a second-order phase transition.
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Research context
OpenAlex topics: Collagen: Extraction and Characterization · Bone and Dental Protein Studies · Orthodontics and Dentofacial Orthopedics
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Taras Shevchenko National University of Kyiv 1 , 64 Volodymyrska Str., Kyiv 01601,
Institute for Safety Problems of Nuclear Power Plants NAS of Ukraine 2 , 36a Kirova Str., Chornobyl, Kyiv Reg. 07270,
Poltava V.G. Korolenko National Pedagogical University 3 , 2 Ostrogradskogo Str., Poltava 36003,
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