Preparation and characterization of GO/ZnO/Ag nanocomposites and their synergistic antibacterial effect on Streptococcus mutans
Source abstract
Abstract
In this study, GO/ZnO/Ag nanocomposites were prepared by a hydrothermal method in one step. The microstructure and surface morphology of the material were analyzed by x-ray diffraction and a scanning electron microscope. The chemical interactions between the available oxygen functional groups of reduced graphene oxide and the inorganic parts (Ag and ZnO) were analyzed by XPS and FTIR. The synergistic antibacterial activity of the nanocomposites against Streptococcus mutans was investigated. It was confirmed that GO/ZnO/Ag could inhibit the growth of S. mutans. The minimal inhibitory concentration and minimum bactericidal concentration of GO/ZnO/Ag on the surface structure of S. mutans were 62.5 and 125 µg/ml, respectively. The material was added to a dental dentin binder, and the modified dentin binder specimens with GO/ZnO/Ag had a significant antibacterial effect against Streptococcus mutans. The results showed that a low dose of GO/ZnO/Ag did not affect the shear bond strength of the dentin binder (P > 0.05), while a high dose of GO/ZnO/Ag decreased the shear bond strength of the dentin binder (P < 0.05). With an increase in GO/ZnO/Ag, the contact angle of the modified dentin binder specimens decreased and the hydrophilicity increased. The nanocomposites can not only be used as antibacterial agents but also have potential applications in biomedical fields.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Graphene and Nanomaterials Applications · Scientific and Engineering Research Topics · Nanoparticles: synthesis and applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
School of Stomatology, Jiamusi University 1 , Jiamusi, Heilongjiang, People’s Republic of China
Department of Stomatology, Baicheng Medical College 2 , Jilin, People’s Republic of China
College of Pharmacy, Jiamusi University 3 , Jiamusi, Heilongjiang, People’s Republic of China
Experimental Animal Center, Jiamusi University 4 , Jiamusi, Heilongjiang, People’s Republic of China
Funding
Project Doctoral Special Research Fund of Jiamusi University · Scientific Research Project of Health and Family Planning Commission in Heilongjiang Province
References (26)
Show source-provided references
1. Toxicity mechanisms in Escherichia coli vary for silver nanoparticles and differ from ionic silver10.1021/nn4044047 ↗
2. Advances of nanomaterial applications in oral and maxillofacial tissue regeneration and disease treatment10.1002/wnan.1669 ↗
3. Graphene-based antibacterial paper10.1021/nn101097v ↗
4. Synthesis of ZnO nanoparticles-decorated spindle-shaped graphene oxide for application in synergistic antibacterial activity10.1016/j.jphotobiol.2018.04.048 ↗
5. Flower-like CuS/graphene oxide with photothermal and enhanced photocatalytic effect for rapid bacteria-killing using visible light10.1007/s12598-021-01759-4 ↗
6. Silver-modified graphene oxide nanosheets for antibacterial performance of bone scaffold10.1063/5.0079975 ↗
7. FDA, http://ecfr.gpoaccess.gov/cgi/t/text/textidx?c=ecfr&sid=786bafc6f6343634fbf79fcdca7061e1&rgn=div5&view=text&node=21:3.0.1.1.13&idno=21#21:3.0.1.1.13.9, 2011.
8. Superior antibacterial activity of zinc oxide/graphene oxide composites originating from high zinc concentration localized around bacteria10.1021/am4053317 ↗
9. Antimicrobial activity of nanoparticulate metal oxides against peri-implantitis pathogens10.1016/j.ijantimicag.2012.04.012 ↗
10. Significance of polymethylmethacrylate (PMMA) modification by zinc oxide nanoparticles for fungal biofilm formation10.1016/j.ijpharm.2016.06.052 ↗
11. An updated review on silver nanoparticles in biomedicine10.3390/nano10112318 ↗
12. Silver nanoparticles biosynthesis, characterization, antimicrobial activities, applications, cytotoxicity and safety issues: An updated review10.3390/nano11082086 ↗
13. Green preparation of Ag-ZnO-rGO nanoparticles for efficient adsorption and photodegradation activity10.1016/j.colsurfa.2019.124011 ↗
14. Anti-biofilm activity and food packaging application of room temperature solution process based polyethylene glycol capped Ag-ZnO-graphene nanocomposite10.1016/j.msec.2018.06.009 ↗
15. Graphene oxide decorated with zinc oxide nanoflower, silver and titanium dioxide nanoparticles: Fabrication, characterization, DNA interaction, and antibacterial activity10.1039/c8ra09788g ↗
16. Polymer-assisted freeze-drying synthesis of Ag-doped ZnO nanoparticles with enhanced photocatalytic activity10.1016/j.ceramint.2018.09.195 ↗
17. Synthesis, characterization and antibacterial activity of Ag incorporated ZnO–graphene nanocomposites10.1039/c6ra14808e ↗
18. Wet-chemically prepared low-dimensional ZnO/Al2O3/Cr2O3 nanoparticles for xanthine sensor development using an electrochemical method10.1039/c8ra01734d ↗
19. Antibacterial property of composites of reduced graphene oxide with nano-silver and zinc oxide nanoparticles synthesized using a microwave-assisted approach10.3390/ijms20215394 ↗
20. One-pot sol–gel synthesis of reduced graphene oxide uniformly decorated zinc oxide nanoparticles in starch environment for highly efficient photodegradation of methylene blue10.1039/c4ra16767h ↗
21. Graphene oxide-modified ZnO particles: Synthesis, characterization, and antibacterial properties10.2147/IJN.S88319 ↗
22. The synthesis and properties of ZnO–graphene nano hybrid for photodegradation of organic pollutant in water10.1016/j.matchemphys.2011.11.085 ↗
23. Facile synthesis and application of Ag-chemically converted graphene nanocomposite10.1007/s12274-010-1037-x ↗
24. Versatile graphene oxide decorated by star shaped zinc oxide nanocomposites with superior adsorption capacity and antimicrobial activity10.1016/j.jsamd.2018.02.002 ↗
25. Fabrication of Ag/ZnO/reduced graphene oxide nanocomposite for SERS detection and multiway killing of bacteria10.1016/j.jallcom.2016.10.241 ↗
26. Fabrication of Ag/ZnO reduced graphene oxide nanocomposite for SERS detection and multiway killing of bacteria10.1016/j.jallcom.2016.10.241 ↗