journal article·2017-05-01Open access

Three-dimensional sensitivity mapping of a handheld magnetic probe for sentinel lymph node biopsy

Akihiro Kuwahata, Shinichi Chikaki, Aslı Ergin, Miki Kaneko, Moriaki Kusakabe, Masaki Sekino

AIP Advances· Volume 7· Issue 5

Abstract

An experimental apparatus for three-dimensional sensitivity mapping of a handheld magnetic probe with a permanent magnet and a Hall sensor was developed. To optimize the shapes and sizes of the magnets, the sensitivity mappings of two types of magnets, column- and cone-type magnets, were evaluated by the experimental apparatus. The longitudinal sensitivities of column and cone types are 8 and 9 mm, respectively, for 5 μL of magnetic nanoparticles. The measured longitudinal sensitivities agree well with the sensitivities calculated by the finite element method. Furthermore, the maximum lateral resolutions of column and cone types are 4.1 and 3.7 mm, respectively. In terms of the directionality, the sensitivities of column and cone types of the angle of 90° with respect to the probe axis fall approximately to 72% and 50% at 6 mm distance from the probe head, indicating that the cone type has high directionality due to its sharp shape. The measurement of sensitivity mapping revealed that the characteristics of the cone-type magnet are superior to that of the column-type magnet for the identification of sentinel lymph nodes.
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Research context

OpenAlex topics: Characterization and Applications of Magnetic Nanoparticles · Salivary Gland Tumors Diagnosis and Treatment · Biosensors and Analytical Detection

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

The University of Tokyo 1 Graduate School of Engineering, , Tokyo, 113-8656, Japan

The University of Tokyo 2 Graduate School of Agricultural and Life Sciences, , 113-8656, Japan

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