journal article·2016-09-01Open access

Facile biosynthesis of Ag-NPs using Otostegia limbata plant extract: Physical characterization and auspicious biological activities

Rizwan Kausar, Muhammad Ashraf Shaheen, Qaisar Maqbool, Sania Naz, Mudassar Nazar, Fazal Abbas, Talib Hussain, Umer Younas, Muhammad Fahad Shams

AIP Advances· Volume 6· Issue 9

Abstract

Silver nanoparticles (Ag-NPs) synthesized through reduction by Otostegia limbata green extract are, hereby, reported for the first time. It is very interesting to observe that in this case, O. limbata plant extract acts as a strong chelating agent in Ag-NPs formation through AgNO3. Scanning electron microscope (SEM) studies expose that Ag-NPs formation is highly homogenous and spherical with mean particle size of 32±0.8 nm. A typical Ag absorption peak has been observed at 419 nm by ultra violet (UV)-visible spectroscopy which have endorsed the successful formation of single phase Ag-NPs. X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR) examination further validates the crystalline pure phase structure of Ag-NPs. Promising results have been recorded against protein kinase inhibition assay and antibacterial assay having prominent pathogenic strains. Our present study explores that biosynthesized eco-friendly Ag-NPs have great potential, in the future, for anticancer drug development with wide range pharmaceutical applications.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Nanoparticles: synthesis and applications · Laser-Ablation Synthesis of Nanoparticles · Quantum Dots Synthesis And Properties

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

University of Sargodha 1 Department of Chemistry, , Sargodha 40100, Pakistan

Virtual University of Pakistan 2 Department of Biotechnology, , Lahore 54000, Pakistan

University of Chakwal (UOC) 3 Interdisciplinary Research Organization, , Chakwal 48800, Pakistan

Preston University 4 Preston Institute of Nano Science and Nanotechnology (PINSAT), , Islamabad 44000, Pakistan

International Islamic University Islamabad (IIUI) 5 Department of Physics, , Islamabad 44000, Pakistan

National Institute of Vacuum Science and Technology (NINVAST) 6 , Islamabad 44000, Pakistan

References (37)

Show source-provided references
1. Perspectives and opportunities for nanomedicine in the management of atherosclerosis10.1038/nrd3578 ↗
2. Magnetic properties of cubic FeCo nanoparticles with anisotropic long chain structure10.1063/1.4945042 ↗
3. Multiresistant pathogens–a challenge for clinicians10.1055/s-0033-1350885 ↗
4. The progress of silver nanoparticles in the antibacterial mechanism, clinical application and cytotoxicity10.1007/s11033-012-1792-8 ↗
5. Challenges in development of nanoparticle-based therapeutics10.1208/s12248-012-9339-4 ↗
6. Shape-controlled synthesis of gold and silver nanoparticles10.1126/science.1077229 ↗
7. Eco-friendly green synthesis, structural and photoluminescent studies of CeO2: Eu3+ nanophosphors using E. tirucalli plant latex10.1016/j.jallcom.2014.05.101 ↗
8. Titanium dioxide nanomaterials: Synthesis, properties, modifications, and applications10.1021/cr0500535 ↗
9. Size- and shape-controlled synthesis of bismuth nanoparticles10.1021/cm8004425 ↗
10. Cytotoxicity of gold nanoparticles10.1016/B978-0-12-391858-1.00012-5 ↗
11. Polyhedral silver nanocrystals with distinct scattering signatures10.1002/anie.200601277 ↗
12. Green synthesis of metal nanoparticles using plants10.1039/c1gc15386b ↗
13. The greener synthesis of nanoparticles10.1016/j.tibtech.2013.01.003 ↗
14. Rapid synthesis of Au, Ag, and bimetallic Au core–Ag shell nanoparticles using Neem (Azadirachta indica) leaf broth10.1016/j.jcis.2004.03.003 ↗
15. Synthesis of gold nanotriangles and silver nanoparticles using Aloevera plant extract10.1021/bp0501423 ↗
16. Solventless synthesis and optical properties of Au and Ag nanoparticles using Camellia sinensis extract10.1016/j.matlet.2008.01.138 ↗
17. Synthesis of plant-mediated gold nanoparticles and catalytic role of biomatrix-embedded nanomaterials10.1021/es062929a ↗
18. Antibacterial activity of Otostegia limbata
19. Antioxidant and free radical scavenging potential of Otostegia limbata
20. Green synthesis of silver nanoparticles using Capsicum annuum L. extract10.1039/b615357g ↗
21. Green synthesis of silver nanoparticles using Azadirachta indica aqueous leaf extract10.1016/j.jrras.2015.06.006 ↗
22. Green synthesis of silver nanoparticles and characterization of their inhibitory effects on AGEs formation using biophysical techniques10.1038/srep20414 ↗
23. Green synthesis and characterization of silver nanoparticles using Ferula latisecta leaf extract and their application as a catalyst for the safe and simple one-pot preparation of spirooxindoles in water10.1039/C5NJ02656C ↗
24. Surface plasmon spectroscopy of nanosized metal particles10.1021/la9502711 ↗
25. Ultrastructures of silver nanoparticles biosynthesized using endophytic fungi10.1016/j.jmau.2014.10.004 ↗
26. Effect of biologically synthesized silver nanoparticles on Staphylococcus aureus biofilm quenching and prevention of biofilm formation10.1049/iet-nbt.2011.0061 ↗
27. Preparation of samarium oxide nanoparticles and its catalytic activity on the esterification10.1016/S0254-0584(01)00594-6 ↗
28. Nanoparticle-mediated cellular response is size-dependent10.1038/nnano.2008.30 ↗
29. Protein kinase activities in cell-free extracts of Streptomyces coelicolor A3(2)10.1016/0300-9084(89)90117-X ↗
30. Effects of protein kinase inhibitors on in vitro protein phosphorylation and cellular differentiation of Streptomyces griseus10.1007/BF00277132 ↗
31. Pharmacological inhibitors of glycogen synthase kinase 310.1016/j.tips.2004.07.006 ↗
32. Does the antibacterial activity of silver nanoparticles depend on the shape of the nanoparticle? A study of the gram-negative bacterium Escherichia coli10.1128/AEM.02218-06 ↗
33. Size-dependent bacterial growth inhibition and mechanism of antibacterial activity of zinc oxide nanoparticles10.1021/la104825u ↗
34. A review of the antibacterial effects of silver nanomaterials and potential implications for human health and the environment10.1007/s11051-010-9900-y ↗
35. Effect of surfactants and polymers on stability and antibacterial activity of silver nanoparticles (NPs)10.1021/jp711616v ↗
36. The bactericidal effect of silver nanoparticles10.1088/0957-4484/16/10/059 ↗
37. Silver nanoparticles: Mechanism of antimicrobial action, synthesis, medical applications, and toxicity effects10.1186/2228-5326-2-32 ↗