journal article·2016-04-01Open access

A normally-closed piezoelectric micro-valve with flexible stopper

Song Chen, Song Lu, Yong Liu, Jiantao Wang, Xiaochao Tian, Guojun Liu, Zhigang Yang

AIP Advances· Volume 6· Issue 4

Abstract

In the field of controlled drug delivery system, there are still many problems on those reported micro-valves, such as the small opening height, unsatisfactory particle tolerance and high cost. To solve the above problems, a novel normally-closed piezoelectric micro-valve is presented in this paper. The micro-valve was driven by circular unimorph piezoelectric vibrator and natural rubber membrane with high elasticity was used as the valve stopper. The small axial displacement of piezoelectric vibrator can be converted into a large stroke of valve stopper based on hydraulic amplification mechanism. The experiment indicates that maximum hydraulic amplification ratio is up to 14, and the cut-off pressure of the micro-valve is 39kPa in the case of no working voltage. The presented micro valve has a large flow control range (ranging from 0 to 8.75mL/min).
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Microfluidic and Capillary Electrophoresis Applications · Microfluidic and Bio-sensing Technologies · Electrohydrodynamics and Fluid Dynamics

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Jilin University 1 School of Mechanical Science and Engineering, , Changchun City 130025, Jilin, China

Changchun University 2 School of mechanical and Vehicular Engineering, , Changchun City 130022, Jilin, China

Funding

National Natural Science Foundation of China

References (20)

Show source-provided references
1. Advanced materials and processing for drug delivery: The past and the future10.1016/j.addr.2012.10.003 ↗
2. Design and test of a high-performance piezoelectric micropump for drug delivery10.1016/j.sna.2004.12.002 ↗
3. A low power, microvalve regulated architecture for drug delivery systems10.1007/s10544-009-9372-y ↗
4. In vitro measurement of flow rate variability in neonatal IV therapy with and without the use of check valves10.3233/NPM-1475213 ↗
5. Compact, power-efficient architectures using microvalves and microsensors, for intrathecal, insulin, and other drug delivery systems10.1016/j.addr.2012.05.002 ↗
6. Design and simulation of an implantable medical drug delivery system using microelectrome-chanical systems technology10.1016/S0924-4247(01)00680-X ↗
7. A novel linear piezoelectric actuator with two working principles of standing and traveling wave vibration mode10.1063/1.4933435 ↗
8. A slim type microvalve driven by PZT films10.1016/j.sna.2004.12.005 ↗
9. Performance of modified pulse-operated piezoelectric valves for the gas inlet system of RFX10.1016/j.fusengdes.2007.06.020 ↗
10. Piezoelectric unimorph valve assembled on an LTCC substrate10.1016/j.sna.2008.11.025 ↗
11. Structure and characterization of a planar normally closed bulk-micromachined piezoelectric valve for fuel cell applications10.1016/j.sna.2004.11.037 ↗
12. MEMS-based hydraulic displacement amplification mechanism with completely encapsulated liquid10.1016/j.sna.2009.07.002 ↗
13. Dynamic Characteristics of a Hydraulic Amplification Mechanism for Large Displacement Actuators Systems10.3390/s100402946 ↗
14. A Piezoelectric Microvalve for Compact High-Frequency, High-Differential Pressure Hydraulic Micropumping Systems10.1109/JMEMS.2002.807471 ↗
15. Fabrication of a high frequency piezoelectric microvalve10.1016/j.sna.2003.10.013 ↗
16. Novel approaches to particle tolerant valves for use in drug delivery systems10.1016/j.sna.2004.08.007 ↗
17. Energy Optimized Valves with Low Leakage Rates
18. A solid hydraulically amplified piezoelectric microvalve10.1088/0960-1317/21/9/095003 ↗
19. Polymer actuator valves toward controlled drug delivery application10.1016/j.bios.2005.10.020 ↗
20. Y Liu, PhD Thesis, Jilin University, 2012.