Advances in ultrafast time resolved fluorescence physics for cancer detection in optical biopsy
Source abstract
Abstract
We discuss the use of time resolved fluorescence spectroscopy to extract fundamental kinetic information on molecular species in tissues. The temporal profiles reveal the lifetime and amplitudes associated with key active molecules distinguishing the local spectral environment of tissues. The femtosecond laser pulses at 310 nm excite the tissue. The emission profile at 340 nm from tryptophan is non-exponential due to the micro-environment. The slow and fast amplitudes and lifetimes of emission profiles reveal that cancer and normal states can be distinguished. Time resolved optical methods offer a new cancer diagnostic modality for the medical community.
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Research context
OpenAlex topics: Optical Imaging and Spectroscopy Techniques · Advanced Fluorescence Microscopy Techniques · Spectroscopy Techniques in Biomedical and Chemical Research
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
University of New York Institute for Ultrafast Spectroscopy and Lasers, Departments of Physics and Electrical Engineering, The City College of the City , 160 Convent Avenue, New York, NY 10031, USA
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