journal article·2017-12-01Open access

Stability of CTL immunity pathogen dynamics model with capsids and distributed delay

A. M. Elaiw, N. H. AlShamrani, A. S. Alofi

AIP Advances· Volume 7· Issue 12

Abstract

In this paper, a pathogen dynamics model with capsids and saturated incidence has been proposed and analyzed. Cytotoxic T Lymphocyte (CTL) immune response and two distributed time delays have been incorporated into the model. The nonnegativity and boundedness of the solutions of the proposed model have been shown. Two threshold parameters which fully determine the existence and stability of the three steady states of the model have been computed. Using the method of Lyapunov function, the global stability of the steady states of the model has been established. The theoretical results have been confirmed by numerical simulations.
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Research context

OpenAlex topics: Mathematical and Theoretical Epidemiology and Ecology Models · Evolution and Genetic Dynamics · Fractional Differential Equations Solutions

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Mathematics, Faculty of Science, King Abdulaziz University , P.O. Box 80203, Jeddah 21589, Saudi Arabia

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