journal article·2017-02-01Open access

Laser heating of metallic nanoparticles for photothermal ablation applications

Xiaoming Liu, Guangshuai Shan, Junsheng Yu, Wei Yang, Zhaodi Ren, Xiaohui Wang, Xi Xie, Hui-jiuan Chen, Xiaodong Chen

AIP Advances· Volume 7· Issue 2

Abstract

In order to search for a suitable frequency and material with higher photothermal efficacy for hyperthermia application in cancer treatment, a comparative study on laser heating of Au/Ag nanoparticles and Ag nanowires has been conducted. It is found that gold nanoparticles are more photothermal efficient in comparison with silver nanoparticles and silver nanowires at 450nm and 532 nm. Gold nanoparticles are more heated by 532 nm laser than 450 nm laser. In contrast, silver nanoparticles show slightly less temperature rise at 532 nm than 450 nm laser. For silver nanowires, no significant photothermal effect has been observed. Size-dependent effect study indicates that the absorption efficiency of single gold nanoparticles of larger diameter is higher than that of smaller diameter, in the diameter range of 0-50nm. A mathematical model for describing the heating profile in the heating sample has been built. The mathematical model can be utilized to predict the optimal treatment size of tumor.
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Research context

OpenAlex topics: Gold and Silver Nanoparticles Synthesis and Applications · Laser-Ablation Synthesis of Nanoparticles · Photoacoustic and Ultrasonic Imaging

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Beijing University of Posts and Telecommunications 1 School of Electronic Engineering, , Beijing 100876, China

Sun Yat-Sen University 2 School of Electronics and Information Technology, State Key Lab of Optoelectronic Materials and Technologies, Guangdong Province Key Laboratory of Display Materials and Technologies, SYSU-CMU Shunde International Joint Research Institute, , Guangzhou 510275, China

Queen Mary University of London 3 School of Electronic Engineering and Computer Science, , London E1 4NS, United Kingdom

Funding

Chinese Postal doctoral Science Fundation · The 100 Talents program of Sun Yat-Sen University · The fund from Shunde Government, Guangdong Province · National Natural Science Foundation of China

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