DNA-decorated carbon nanotube-based FETs as ultrasensitive chemical sensors: Discrimination of homologues, structural isomers, and optical isomers
Source abstract
Abstract
We have explored the abilities of all-electronic DNA-carbon nanotube (DNA-NT) vapor sensors to discriminate very similar classes of molecules. We screened hundreds of DNA-NT devices against a panel of compounds chosen because of their similarities. We demonstrated that DNA-NT vapor sensors readily discriminate between series of chemical homologues that differ by single methyl groups. DNA-NT devices also discriminate among structural isomers and optical isomers, a trait common in biological olfactory systems, but only recently demonstrated for electronic FET based chemical sensors.
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Research context
OpenAlex topics: Advanced Chemical Sensor Technologies · Advanced biosensing and bioanalysis techniques · Biochemical Analysis and Sensing Techniques
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
University of Pennsylvania 1 Department of Physics and Astronomy, , Philadelphia, Pennsylvania 19104, USA
Monell Chemical Senses Center 2 , Philadelphia, Pennsylvania 19104, USA
University of Pennsylvania 3 Department of Dermatology, , Philadelphia, Pennsylvania 19104 USA
Princeton University 4 Princeton Neuroscience Institute, Department of Molecular Biology, , Princeton, New Jersey 08544, USA
Funding
"National Science Foundation"
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