Hydrogel: A potential therapeutic material for bone tissue engineering
Source abstract
Abstract
Current surgical treatments and material applications are not ideal for the treatment of orthopedic clinical injuries, such as large bone defects, cartilage defects, and vascular tendon adhesions that occur after repair. With the continuous development of tissue engineering technology, hydrogels have become important medical biomaterials. Hydrogels are three-dimensional hydrophilic network structures composed of cross-linked polymer chains. They are a new kind of polymeric material for the treatment of orthopedic diseases. Hydrogels have good biocompatibility, biodegradability, drug-carrying capacity, and controllable drug release ability and are less toxic than nanoparticle carriers. They have been widely used in wound repair, guided tissue regeneration, bacteriostasis, hemostasis, postoperative adhesion prevention, drug delivery, and 3D printing. These characteristics can be used to develop a variety of treatments for different diseases. This paper focuses on the innovative progress of hydrogels in promoting and improving bone, cartilage, tendon, and soft tissue regeneration in orthopedic clinical applications. Current and prospective applications of hydrogels in the field of orthopedics are discussed herein.
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Research context
OpenAlex topics: 3D Printing in Biomedical Research · Bone Tissue Engineering Materials · Electrospun Nanofibers in Biomedical Applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Plastic Surgery, First Affiliated Hospital of Bengbu Medical College 1 , Bengbu 233004, People’s Republic of China
School of Life Science, Bengbu Medical College 2 , Bengbu 233030, People’s Republic of China
Anhui Province Key Laboratory of Tissue Transplantation, Bengbu Medical College 3 , 2600 Donghai Road, Bengbu 233030, People’s Republic of China
Department of Orthopedics, First Affiliated Hospital of Bengbu Medical College 4 , Bengbu 233004, People’s Republic of China
Funding
Natural Science Foundation of Anhui Province · National Natural Science Foundation of China · Key Program of Anhui Educational Committee · Scientific Research Foundation of Bengbu Medical College · Translational Medicine Key Projects of Bengbu Medical College · Scientific Research Innovation Team of Bengbu Medical College
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