Glomage : A Multimodal Platform for High‐Content Morphological and RNA Profiling of Glomeruli in Zebrafish and Mouse Models (Adv. Sci. 39/2026)

Glomage - A Platform for 3D Analyses of Kidney Glomeruli This cover image depicts a depth-color-coded projection of the filtration barrier in an isolated kidney glomerulus of a zebrafish larva. The glomerulus is a highly specialized compartment enabling selective blood filtration through a precisely organized cellular architecture. At its core, the transmembrane protein nephrin forms the slit diaphragm between interdigitating podocyte foot processes, maintaining filtration barrier integrity. In their Research Article (DOI: 10.1002/advs.202523662), Maximilian Schindler, Nicole Endlich, and colleagues present Glomage as a powerful multimodal imaging platform for structural and molecular profiling of glomeruli in zebrafish and mouse models. Glomage is an innovative and scalable cross-species approach that opens new dimensions in glomerular research.