Lyophilized Synthetic Platelets: In Vitro Characterization and in Vivo Evaluation in Mouse Thrombocytopenia Model (Adv. Sci. 38/2026)

Lyophilized Synthetic Platelets The image foreground depicts the artist's vision of liposome-based synthetic platelet nanoconstructs where the nanoparticles are surface-decorated by three different synthetic peptide ligands that combinatorially mimic the primary hemostatic functions of platelets. The image background shows a confocal microscopy image of clot formed involving the synthetic platelet nanoconstructs, with platelets in green, fibrin in red and synthetic platelets in cyan. More details can be found in the Research Article by Christa L. Pawlowski, Anirban Sen Gupta, and co-workers (DOI: 10.1002/advs.202600002).