journal article·2026-04Open access

A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells (Adv. Sci. 22/2026)

Jose Bolaños‐Cardet, Sara Pugliese, Jordi Bruna, Daniel Ruiz‐Molina, Salvio Suárez‐García, Victor J. Yuste

Advanced Science· Volume 13· Issue 22

Abstract

Mussel-Inspired Bioadhesive Patch A mussel-inspired bioadhesive membrane anchors to brain tissue following a glioblastoma resection. Driven by polyphenol redox chemistry of polyphenols, the patch generates reactive oxygen species to selectively kill adjacent glioblastoma cells while preserving surrounding healthy tissue. This platform combines robust wet adhesion with sustained local therapeutic activity, offering a promising strategy to prevent tumor recurrence while minimizing systemic side effects. More details can be found in the Research Article by Daniel Ruiz-Molina, Salvio Suárez-García, Victor J. Yuste, and co-workers (DOI: 10.1002/advs.202510658).
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Research context

OpenAlex topics: Nanoplatforms for cancer theranostics · 3D Printing in Biomedical Research · Cancer Research and Treatments

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