ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling (Adv. Sci. 16/2026)

ROS at the Tipping Point This image depicts pro-oxidant-induced reactive oxygen species (ROS) as a double-edged blade or shield that fine-tunes cellular fate at the tipping point between protection and destruction, with the ERM inhibitors NSC305787 and NSC668394 representing a class of pro-oxidant ferroptosis inhibitors. More details can be found in the Research Article by Junqi Huang, Ting Gang Chew, Yunmiao Guo, Lijuan Pang, and co-workers (DOI: 10.1002/advs.202513310).