journal article·2026-02Open access

A Hydrodynamic Bioreactor for High‐Yield Production of Extracellular Vesicles from Stem Cell Spheroids with Defined Cargo Profiling (Adv. Sci. 10/2026)

Solène Lenoir, Elliot Thouvenot, Giacomo Gropplero, Léonie Dec, Damarys Loew, Clotilde Théry, Jose E Perez, Claire Wilhelm

Advanced Science· Volume 13· Issue 10

Abstract

Extracellular Vesicles In the rotating baffled tube, gentle waves of alternating flow bring single stem cells together into spheroids, which become momentarily trapped in turbulent micro-eddies that boost the release of extracellular vesicles carrying a distinct hydrodynamic (blue) molecular imprint. More details can be found in the Research Article by Claire Wilhelm and co-workers (DOI: 10.1002/advs.202510607).
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Extracellular vesicles in disease · Innovative Microfluidic and Catalytic Techniques Innovation · Lipid Membrane Structure and Behavior

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

References

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