Iron Single‐Atom Catalyzed N‐Alkylation of Amines with Alcohols via Solvent‐Free Borrowing Hydrogen Strategy (Adv. Sci. 46/2025)

Iron Single-Atom Catalyzed N-Alkylation of Amines This cover illustrates the solvent-free N-alkylation of amines with alcohols over an N-doped graphene-supported iron single-atom catalyst. The artwork highlights the catalytic Fe–N4 interface where efficient hydride transfer takes place. The catalyst delivers outstanding catalytic efficiency along with record turnover number (1032.7) and turnover frequency (413.1 h−1) for the N-alkylation reaction, outperforming all previously reported systems. More details can be found in the Research Article by Radek Zboril, Yifeng Wang, Manoj B. Gawande, and co-workers (DOI: 10.1002/advs.202507915).