Nutritional c‐Fos Induction Rewires Hepatic Metabolism and Can Promote Obesity‐Associated Hepatocellular Carcinoma (Adv. Sci. 47/2025)

Nutritional c-Fos Induction The cover image illustrates the role of the transcription factor c-Fos in liver physiology and its alter ego in liver dysfunction in obesity. As in a comic story, the blue superhero represents the “good” c-Fos in the healthy liver and the effect of an obesogenic diet that turns him into an “evil” version. More details can be found in the Research Article by Esteban N. Gurzov and co-workers (DOI: 10.1002/advs.202509755). The cartoon is an original design by Dr. Eduardo H. Gilglioni.