journal article·2025-11Open access

A Prion‐Like Domain in EBV EBNA1 Promotes Phase Separation and Enables SRRM1 Splicing (Adv. Sci. 41/2025)

Xiaoyue Zhang, Zhengshuo Li, Run Zheng, Xiang Zheng, Jia Wang, Can Liu, Yangge Wu, Yuqing Wen, Chunlin Ou, Songqing Fan, Chenxiao Xu, Junrui Tian, Qun Yan, Hao Nan, Xiaodong Xu, Hui Wang, Qiu Peng, Jian Ma

Advanced Science· Volume 12· Issue 41

Abstract

EBV EBNA1 is a Prion-Like Protein Named “EBNA1 PrLD”, the boat plows through the pond, its wake carving a decisive boundary between two fates of EBNA1: the vibrant green lotus leaves, sparse and vital, embody its native, dispersed state; while the fiery orange leaves, clustering densely, mirror the aggregated, pathogenic form, prion. More details can be found in the Research Article by Xiaoyue Zhang, Hui Wang, Qiu Peng, Jian Ma, and co-workers (DOI: 10.1002/advs.202501977).
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Research context

OpenAlex topics: RNA Research and Splicing · RNA regulation and disease · Plant Virus Research Studies

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

References

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