Sugar Functionalized Collagen Material for Local Modulation of Innate Immunity (Adv. Sci. 31/2025)

Local Immunomodulatory Patch The Corradetti and Taraballi Labs join forces to revolutionize implant technology with their groundbreaking local immunotuning patch (LIP). Enhanced with mannose moieties, this collagen patch uniquely targets antigen-presenting cells, shaping an immune-engineered environment around the implant. LIP not only demonstrates powerful anti-inflammatory effects, it also combats methicillin-resistant bacteria, setting a new standard for advanced wound healing and infection control. More details can be found in article number 2415364.