journal article·2025-08Open access

Plasma DNMT1 Activity for Assessing Tumor Burden and Predicting Neoadjuvant Therapy Response in Breast Cancer (Adv. Sci. 31/2025)

Yingran Wang, Guozhi Zhang, Zhizhao Zhang, Mengsi Zhang, Jiao Chen, Ke Wang, Lu Liu, Jing Bao, Ming Chen, Xiaowei Qi, Mingxuan Gao

Advanced Science· Volume 12· Issue 31

Abstract

Plasma DNMT1 Activity The cover depict a sensitive method for detecting DNA methyltransferase 1 (DNMT1) in human plasma, namely DNMT1 identification by variable activity (DIVA). The high sensitivity of this method enables effective tumor burden assessment and neoadjuvant therapy prediction for breast cancer patients. More details can be found in article number 2501064 by Ming Chen, Xiaowei Qi, Mingxuan Gao, and co-workers.
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Research context

OpenAlex topics: Cancer Cells and Metastasis · Cancer Genomics and Diagnostics · Nanoplatforms for cancer theranostics

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