Flavonifractor Plautii or Its Metabolite Desaminotyrosine as Prophylactic Agents for Alleviating Myocardial Ischemia/Reperfusion Injury (Adv. Sci. 21/2025)

Flavonifractor Plautii The image highlights the cardioprotective effects of the gut microbiome bacterium Flavonifractor plautii, symbolized by the seven-colored lotus. Its metabolite DAT, represented by the steam rising from the lotus, conveys cardioprotection to the heart, depicted as Nezha (哪吒), a heroic figure from Chinese mythology. This imagery demonstrates Flavonifractor plautii and DAT as prophylactic therapeutic options for protecting the heart against myocardial ischemia-reperfusion (I/R) injury. More details can be found in article number 2417827 by Jun Wang, Moshi Song, and co-workers. Illustration by Yizhu Wang.