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journal article·2025-06Open access

Identification of Tumor‐Specific Surface Proteins Enables Quantification of Extracellular Vesicle Subtypes for Early Detection of Pancreatic Ductal Adenocarcinoma (Adv. Sci. 21/2025)

Chen Zhao, Zhili Wang, Hyoyong Kim, Hui Kong, Junseok Lee, Jacqueline Ziqian Yang, Anmin Wang, Ryan Y. Zhang, Yong Ju, Jina Kim, Bing Feng, Dejun Liu, Yating Zhang, Zhenfang Wang, Yandong Zhang, Shujing Guo, Dekang Gao, James S. Tomlinson, Renjun Pei, Jipeng Wan, Stephen J. Pandol, Myung‐Shin Sim, Sungyong You, Ding Ma, Shaohua Lu, Na Sun, Hsian‐Rong Tseng, Yazhen Zhu

Advanced Science· Volume 12· Issue 21
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Source abstract

Abstract

Early Pancreatic Cancer Detection Na Sun, Hsian-Rong Tseng, Yazhen Zhu, and colleagues have developed a simple, noninvasive test for early pancreatic cancer detection. Their approach uses click chemistry to capture extracellular vesicles (EVs) released by cancer cells. Once isolated, these cancer EVs are analyzed with a standard PCR machine to measure their mRNA content, providing a promising biomarker for pancreatic cancer. More details can be found in article number 2414982.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Extracellular vesicles in disease

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