Correlation Between Fecal Microbiota and Corticosteroid Responsiveness in Primary Immune Thrombocytopenia: an Exploratory Study (Adv. Sci. 22/2025)
Source abstract
Abstract
Immune Thrombocytopenia Immune thrombocytopenia (ITP) is characterized by splenic platelet destruction and dysfunctional megakaryocyte maturation. Emerging research demonstrates that machine learning frameworks analyzing gut microbiome profiles and clinical parameters can reliably forecast treatment responses to corticosteroids through microbiota-immune axis modulation. This predictive modeling approach enables personalized therapeutic strategies in ITP care, advancing precision hematology through computational biomarker integration. More details can be found in article number 2410417 by Xiao-hui Zhang and co-worders.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Platelet Disorders and Treatments · Lipid metabolism and disorders · Blood groups and transfusion
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References
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