DNA Origami‐Cyanine Nanocomplex for Precision Imaging of KRAS‐Mutant Pancreatic Cancer Cells (Adv. Sci. 19/2025)
Source abstract
Abstract
DNA Origami-Cyanine Nanocomplex The internalization of DNA origami-cyanine nanocomplex via micropinocytosis, characterized by membrane ruffling and vesicle formation, is significantly enhanced in pancreatic cancer cells with KRAS mutation. In article number 2410278 by Jong Hyun Choi, Bumsoo Han, and co-workers, a new molecular imaging method is proposed based on this finding to selectively visualize pancreatic cancer cells in desmoplastic tumors.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Nanoplatforms for cancer theranostics · Advanced biosensing and bioanalysis techniques
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